Publications (32) RUBÉN MARTÍN ESCOLANO publications

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2023

  1. Identification of Aryl Polyamines Derivatives as Anti-Trypanosoma cruzi Agents Targeting Iron Superoxide Dismutase †

    Pharmaceutics, Vol. 15, Núm. 1

2022

  1. 5-Nitroindazole derivatives as potential therapeutic alternatives against Acanthamoeba castellanii

    Acta Tropica, Vol. 232

  2. An Updated View of the Trypanosoma cruzi Life Cycle: Intervention Points for an Effective Treatment

    ACS infectious diseases, Vol. 8, Núm. 6, pp. 1107-1115

  3. Biological characteristics of the Trypanosoma cruzi Arequipa strain make it a good model for Chagas disease drug discovery

    Acta Tropica, Vol. 236

2021

  1. Heterocyclic Diamines with Leishmanicidal Activity

    ACS Infectious Diseases, Vol. 7, Núm. 12, pp. 3168-3181

  2. In vitro anti-Acanthamoeba activity of flavonoid glycosides isolated from Delphinium gracile, D. staphisagria, Consolida oliveriana and Aconitum napellus

    Parasitology, Vol. 148, Núm. 11, pp. 1392-1400

  3. Library of selenocyanate and diselenide derivatives as in vivo antichagasic compounds targeting trypanosoma cruzi mitochondrion

    Pharmaceuticals, Vol. 14, Núm. 5

  4. Repurposing in vitro approaches for screening anti-parasitic drugs against the brain-eating amoeba Naegleria fowleri

    International Journal for Parasitology: Drugs and Drug Resistance, Vol. 17, pp. 204-212

  5. Selenium Derivatives as Promising Therapy for Chagas Disease: In Vitro and in Vivo Studies

    ACS Infectious Diseases, Vol. 7, Núm. 6, pp. 1727-1738

2020

  1. Assessing the effectiveness of AS-48 in experimental mice models of Chagas' disease

    Journal of Antimicrobial Chemotherapy, Vol. 75, Núm. 6, pp. 1537-1545

  2. Chagas Disease: Current View of an Ancient and Global Chemotherapy Challenge

    ACS Infectious Diseases, Vol. 6, Núm. 11, pp. 2830-2843

  3. In Vivo Biological Evaluation of a Synthetic Royleanone Derivative as a Promising Fast-Acting Trypanocidal Agent by Inducing Mitochondrial-Dependent Necrosis

    Journal of Natural Products, Vol. 83, Núm. 12, pp. 3571-3583

  4. In vitro evaluation of leishmanicidal properties of a new family of monodimensional coordination polymers based on diclofenac ligand

    Polyhedron, Vol. 184

  5. Repositioning of leishmanicidal [1,2,3]Triazolo[1,5-a]pyridinium salts for Chagas disease treatment: Trypanosoma cruzi cell death involving mitochondrial membrane depolarisation and Fe-SOD inhibition

    Parasitology Research, Vol. 119, Núm. 9, pp. 2943-2954

2019

  1. A step towards development of promising trypanocidal agents: Synthesis, characterization and in vitro biological evaluation of ferrocenyl Mannich base-type derivatives

    European Journal of Medicinal Chemistry, Vol. 163, pp. 569-582

  2. Antichagasic profile of a Series of Mannich Base-Type Derivatives: Design, Synthesis, in vitro Evaluation, and Computational Studies Involving Iron Superoxide Dismutase

    ChemistrySelect, Vol. 4, Núm. 27, pp. 8112-8121

  3. Effective tetradentate compound complexes against leishmania spp. that act on critical enzymatic pathways of these parasites

    Molecules, Vol. 24, Núm. 1

  4. In vitro assessment of 3-alkoxy-5-nitroindazole-derived ethylamines and related compounds as potential antileishmanial drugs

    Bioorganic Chemistry, Vol. 92

  5. Insights into Chagas treatment based on the potential of bacteriocin AS-48

    International Journal for Parasitology: Drugs and Drug Resistance, Vol. 10, pp. 1-8

  6. New polyamine drugs as more effective antichagas agents than benznidazole in both the acute and chronic phases

    European Journal of Medicinal Chemistry, Vol. 164, pp. 27-46