Publicaciones en colaboración con investigadores/as de Instituto de Parasitología y Biomedicina López Neyra (12)

2023

  1. Corrigendum: Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes (Frontiers in Microbiology, (2023), 14, (1149145), 10.3389/fmicb.2023.1149145)

    Frontiers in Microbiology

  2. Role of the RNA-binding protein ZC3H41 in the regulation of ribosomal protein messenger RNAs in trypanosomes

    Parasites & vectors, Vol. 16, Núm. 1, pp. 118

2022

  1. The RNA-binding protein RBP33 dampens non-productive transcription in trypanosomes

    Nucleic Acids Research, Vol. 50, Núm. 21, pp. 12251-12265

2021

  1. An RNA-binding protein complex regulates the purine-dependent expression of a nucleobase transporter in trypanosomes

    Nucleic Acids Research, Vol. 49, Núm. 7

  2. Lead Optimization of 3,5-Disubstituted-7-Azaindoles for the Treatment of Human African Trypanosomiasis

    Journal of Medicinal Chemistry, Vol. 64, Núm. 13, pp. 9404-9430

2020

  1. Medicinal Chemistry Optimization of a Diaminopurine Chemotype: Toward a Lead for Trypanosoma brucei Inhibitors

    Journal of Medicinal Chemistry, Vol. 63, Núm. 17, pp. 9912-9927

  2. Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5- b]pyridazines for the Treatment of Human African Trypanosomiasis

    Journal of Medicinal Chemistry, Vol. 63, Núm. 2, pp. 756-783

  3. Structure-property studies of an imidazoquinoline chemotype with antitrypanosomal activity

    RSC Medicinal Chemistry, Vol. 11, Núm. 8, pp. 950-959

2019

  1. Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-sleeping sickness agents

    PLoS Neglected Tropical Diseases, Vol. 13, Núm. 2

2017

  1. From Cells to Mice to Target: Characterization of NEU-1053 (SB-443342) and Its Analogues for Treatment of Human African Trypanosomiasis

    ACS Infectious Diseases, Vol. 3, Núm. 3, pp. 225-236

  2. Novel 1,2-dihydroquinazolin-2-ones: Design, synthesis, and biological evaluation against Trypanosoma brucei

    Bioorganic and Medicinal Chemistry Letters, Vol. 27, Núm. 16, pp. 3629-3635

2016

  1. The AMPKα1 Pathway Positively Regulates the Developmental Transition from Proliferation to Quiescence in Trypanosoma brucei

    Cell Reports, Vol. 17, Núm. 3, pp. 660-670