Publicaciones (19) Publicaciones de JOSÉ MANUEL RODRÍGUEZ VARGAS

2022

  1. Glioblastoma Cells Counteract PARP Inhibition through Pro-Survival Induction of Lipid Droplets Synthesis and Utilization

    Cancers, Vol. 14, Núm. 3

2021

  1. Selective modulation by PARP-1 of HIF-1α-recruitment to chromatin during hypoxia is required for tumor adaptation to hypoxic conditions

    Redox Biology, Vol. 41

  2. Tankyrases as modulators of pro-tumoral functions: molecular insights and therapeutic opportunities

    Journal of Experimental and Clinical Cancer Research, Vol. 40, Núm. 1

2020

  1. Parp3 promotes astrocytic differentiation through a tight regulation of Nox4-induced ROS and mTorc2 activation

    Cell Death and Disease, Vol. 11, Núm. 11

2019

  1. PARP1 and poly(ADP-ribosyl)ation signaling during autophagy in response to nutrient deprivation

    Oxidative Medicine and Cellular Longevity, Vol. 2019

  2. PARP3 comes to light as a prime target in cancer therapy

    Cell Cycle, Vol. 18, Núm. 12, pp. 1295-1301

  3. PARP3, a new therapeutic target to alter Rictor/mTORC2 signaling and tumor progression in BRCA1-associated cancers

    Cell Death and Differentiation, Vol. 26, Núm. 9, pp. 1615-1630

2017

  1. Expanding functions of ADP-ribosylation in the maintenance of genome integrity

    Seminars in Cell and Developmental Biology, Vol. 63, pp. 92-101

2016

  1. Autophagy requires poly(adp-ribosyl)ation-dependent AMPK nuclear export

    Cell Death and Differentiation, Vol. 23, Núm. 12, pp. 2007-2018

  2. PARP3 controls TGFβ and ROS driven epithelial-to-mesenchymal transition and stemness by stimulating a TG2-Snail-E-cadherin axis

    Oncotarget, Vol. 7, Núm. 39, pp. 64109-64123

  3. Role of Poly(ADP-Ribose) in Catalyzing Starvation-Induced Autophagy

    Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging Volume 10 (Elsevier), pp. 99-118

2015

  1. PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma

    Oncotarget, Vol. 6, Núm. 7, pp. 4790-4803

2013

  1. PARP-1 Regulates Metastatic Melanoma through Modulation of Vimentin-induced Malignant Transformation

    PLoS Genetics, Vol. 9, Núm. 6

  2. Poly(ADP-ribose) signaling in cell death

    Molecular Aspects of Medicine, Vol. 34, Núm. 6, pp. 1153-1167

2012

  1. ROS-induced DNA damage and PARP-1 are required for optimal induction of starvation-induced autophagy

    Cell Research, Vol. 22, Núm. 7, pp. 1181-1198

  2. The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria-mediated apoptosis and DNA damage in p53 mutant leukemic T cells

    International Journal of Cancer, Vol. 130, Núm. 5, pp. 1195-1207

2009

  1. PARP inhibitors: New partners in the therapy of cancer and inflammatory diseases

    Free Radical Biology and Medicine, Vol. 47, Núm. 1, pp. 13-26

  2. PARP-1 is involved in autophagy induced by DNA damage

    Autophagy, Vol. 5, Núm. 1, pp. 61-74

2007

  1. Modulation of transcription by PARP-1: Consequences in carcinogenesis and inflammation

    Current Medicinal Chemistry, Vol. 14, Núm. 11, pp. 1179-1187