QUÍMICA FARMACÉUTICA Y ORGÁNICA
DEPARTAMENTO
JUAN ANTONIO
MARCHAL CORRALES
CATEDRÁTICO DE UNIVERSIDAD
Publicaciones en las que colabora con JUAN ANTONIO MARCHAL CORRALES (45)
2024
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Autologous patient-derived exhausted nano T-cells exploit tumor immune evasion to engage an effective cancer therapy
Molecular Cancer, Vol. 23, Núm. 1
2023
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Lentiviral vectors for inducible, transactivator-free advanced therapy medicinal products: Application to CAR-T cells
Molecular Therapy - Nucleic Acids, Vol. 32, pp. 322-339
2022
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Nanomedicine as a Promising Tool to Overcome Immune Escape in Breast Cancer
Pharmaceutics, Vol. 14, Núm. 3
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Physiological lentiviral vectors for the generation of improved CAR-T cells
Molecular Therapy - Oncolytics, Vol. 25, pp. 335-349
2021
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Design, synthesis, HER2 inhibition and anticancer evaluation of new substituted 1,5-dihydro-4,1-benzoxazepines
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 36, Núm. 1, pp. 1553-1563
2020
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A versatile theranostic nanodevice based on an orthogonal bioconjugation strategy for efficient targeted treatment and monitoring of triple negative breast cancer
Nanomedicine: Nanotechnology, Biology, and Medicine, Vol. 24
2018
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Enhancement of tumor cell death by combining gef gene mediated therapy and new 1,4-benzoxazepin-2,6-dichloropurine derivatives in breast cancer cells
Frontiers in Pharmacology, Vol. 9, Núm. JUL
2017
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1-(Benzenesulfonyl)-1,5-dihydro-4,1-benzoxazepine as a new scaffold for the design of antitumor compounds
Future Medicinal Chemistry, Vol. 9, Núm. 11, pp. 1129-1140
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Antitumoral activity of 1,2-diaminocyclohexane derivatives in breast, colon and skin human cancer cells
Future Medicinal Chemistry, Vol. 9, Núm. 3, pp. 293-302
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Poly(ethylmethacrylate-co-diethylaminoethyl acrylate) coating improves endothelial re-population, bio-mechanical and anti-thrombogenic properties of decellularized carotid arteries for blood vessel replacement
Scientific Reports, Vol. 7, Núm. 1
2015
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P-Nitrobenzenesulfonamides and their fluorescent dansylsulfonamides derived from N-alkylated o-(purine-methyl)anilines as novel antitumour agents
RSC Advances, Vol. 5, Núm. 93, pp. 76615-76619
2014
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Anti-proliferative activity of 2,6-dichloro-9- or 7-(ethoxycarbonylmethyl)- 9H- or 7H-purines against several human solid tumour cell lines
European Journal of Medicinal Chemistry, Vol. 76, pp. 118-124
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HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound
Oncotarget, Vol. 5, Núm. 11, pp. 3590-3606
2013
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Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence
Drug Design, Development and Therapy, Vol. 7, pp. 1301-1313
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Enantiospecific synthesis of heterocycles linked to purines: Different apoptosis modulation of enantiomers in breast cancer cells
Current Medicinal Chemistry, Vol. 20, Núm. 38, pp. 4924-4934
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In vitro nanoparticle-mediated intracellular delivery into human adipose-derived stem cells
Methods in Molecular Biology, Vol. 1058, pp. 41-47
2012
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The selective cytotoxic activity in breast cancer cells by an anthranilic alcohol-derived acyclic 5-fluorouracil O,N-acetal is mediated by endoplasmic reticulum stress-induced apoptosis
European Journal of Medicinal Chemistry, Vol. 50, pp. 376-382
2011
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Anticancer activity and cDNA microarray studies of a (RS)-1,2,3,5- tetrahydro-4,1-benzoxazepine-3-yl]-6-chloro-9H-purine, and an acyclic (RS)-O,N-acetalic 6-chloro-7H-purine
European Journal of Medicinal Chemistry, Vol. 46, Núm. 9, pp. 3802-3809
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New (RS)-benzoxazepin-purines with antitumour activity: The chiral switch from (RS)-2,6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1,2,3,5-tetrahydro-4,1- benzoxazepin-3-yl]-9H-purine
European Journal of Medicinal Chemistry, Vol. 46, Núm. 1, pp. 249-258
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Synthesis and Anticancer Activity of the (R,S)-Benzofused 1,5-Oxathiepine Moiety Tethered to Purines through Alkylidenoxy Linkers
ChemMedChem, Vol. 6, Núm. 10, pp. 1854-1859