QUÍMICA FARMACÉUTICA Y ORGÁNICA
DEPARTAMENTO
FERNANDO
RODRÍGUEZ SERRANO
PROFESOR TITULAR DE UNIVERSIDAD
Publicaciones en las que colabora con FERNANDO RODRÍGUEZ SERRANO (14)
2012
-
The selective cytotoxic activity in breast cancer cells by an anthranilic alcohol-derived acyclic 5-fluorouracil O,N-acetal is mediated by endoplasmic reticulum stress-induced apoptosis
European Journal of Medicinal Chemistry, Vol. 50, pp. 376-382
2011
-
Anticancer activity and cDNA microarray studies of a (RS)-1,2,3,5- tetrahydro-4,1-benzoxazepine-3-yl]-6-chloro-9H-purine, and an acyclic (RS)-O,N-acetalic 6-chloro-7H-purine
European Journal of Medicinal Chemistry, Vol. 46, Núm. 9, pp. 3802-3809
-
New (RS)-benzoxazepin-purines with antitumour activity: The chiral switch from (RS)-2,6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1,2,3,5-tetrahydro-4,1- benzoxazepin-3-yl]-9H-purine
European Journal of Medicinal Chemistry, Vol. 46, Núm. 1, pp. 249-258
2008
-
Anticancer activity of (1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl)-pyrimidines and -purines against the MCF-7 cell line: Preliminary cDNA microarray studies
Bioorganic and Medicinal Chemistry Letters, Vol. 18, Núm. 4, pp. 1457-1460
-
Regiospecific microwave-assisted synthesis and cytotoxic activity against human breast cancer cells of (RS)-6-substituted-7- or 9-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)-7H- or -9H-purines
European Journal of Medicinal Chemistry, Vol. 43, Núm. 8, pp. 1742-1748
-
Synthesis and anticancer activity of (R,S)-9-(2,3-dihydro-1,4-benzoxathiin- 3-ylmethyl)-9H-purines
ChemMedChem, Vol. 3, Núm. 1, pp. 127-135
2007
-
5-fluorouracil derivatives induce differentiation mediated by tubulin and HLA class I modulation
Medicinal Chemistry, Vol. 3, Núm. 3, pp. 233-239
-
6′-Chloro-7- or 9-(2,3-dihydro-5H-4,1-benzoxathiepin-3-yl)-7H- or 9H-purines and their corresponding sulfones as a new family of cytotoxic drugs
Tetrahedron, Vol. 63, Núm. 1, pp. 183-190
-
A synthetic uracil derivative with antitumor activity through decreasing cyclin D1 and Cdk1, and increasing p21 and p27 in MCF-7 cells
Breast Cancer Research and Treatment, Vol. 105, Núm. 3, pp. 237-246
-
Antiproliferative activity, cell-cycle dysregulation, and cellular differentiation: Salicyl- and catechol-derived acyclic 5-fluorouracil O,N-acetals against breast cancer cells
ChemMedChem, Vol. 2, Núm. 12, pp. 1814-1821
2006
-
Differentiation: An encouraging approach to anticancer therapy
Italian Journal of Anatomy and Embryology, Vol. 111, Núm. 1, pp. 45-64
-
Synthesis and anticancer activity studies of novel 1-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)uracil and (6′-substituted)-7- or 9-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)-7H- or 9H-purines
Tetrahedron, Vol. 62, Núm. 50, pp. 11724-11733
2005
-
Synthesis of novel 1-(2,3-dihydro-5H-4,1-benzoxathiepin-3-yl)-uracil and -thymine, and their corresponding S-oxidized derivatives
Tetrahedron, Vol. 61, Núm. 43, pp. 10363-10369
2004
-
Synthesis of tetrahydrobenzoxazepine acetals with electron-withdrawing groups on the nitrogen atom. Novel scaffolds endowed with anticancer activity against breast cancer cells
Tetrahedron, Vol. 60, Núm. 50, pp. 11547-11557