BIOQUÍMICA Y BIOLOGÍA MOLECULAR I
Departamento
Universidad de Zaragoza
Zaragoza, EspañaPublicaciones en colaboración con investigadores/as de Universidad de Zaragoza (14)
2022
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Allosteric Communication in the Multifunctional and Redox NQO1 Protein Studied by Cavity‐Making Mutations
Antioxidants, Vol. 11, Núm. 6
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Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations
Archives of Biochemistry and Biophysics, Vol. 729
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Embedding Biomimetic Magnetic Nanoparticles Coupled with Peptide AS-48 into PLGA to Treat Intracellular Pathogens
Pharmaceutics, Vol. 14, Núm. 12
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Targeting HIF-1α Function in Cancer through the Chaperone Action of NQO1: Implications of Genetic Diversity of NQO1
Journal of Personalized Medicine, Vol. 12, Núm. 5
2021
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Anticancer and structure activity relationship of non-symmetrical choline kinase inhibitors
Pharmaceutics, Vol. 13, Núm. 9
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Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue
Redox Biology, Vol. 46
2020
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Synthesis, biological evaluation, in silico modeling and crystallization of novel small monocationic molecules with potent antiproliferative activity by dual mechanism
European Journal of Medicinal Chemistry, Vol. 207
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The isolated armadillo-repeat domain of Plakophilin 1 is a monomer in solution with a low conformational stability
Journal of Structural Biology, Vol. 211, Núm. 3
2017
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Choline kinase inhibition and docking studies of a series of 6-(benzylthio)-9H-purin-9-yl-pyridinium derivatives
Medicinal Chemistry Research, Vol. 26, Núm. 11, pp. 2809-2815
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Contribution of inducible and neuronal nitric oxide synthases to mitochondrial damage and melatonin rescue in LPS-treated mice
Journal of Physiology and Biochemistry, Vol. 73, Núm. 2, pp. 235-244
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Enhanced vulnerability of human proteins towards disease-associated inactivation through divergent evolution
Human Molecular Genetics, Vol. 26, Núm. 18, pp. 3531-3544
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Site-to-site interdomain communication may mediate different loss-of-function mechanisms in a cancer-associated NQO1 polymorphism
Scientific Reports, Vol. 7
2016
2014
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Choline kinase active site provides features for designing versatile inhibitors
Current Topics in Medicinal Chemistry, Vol. 14, Núm. 23, pp. 2684-2693