Publicaciones en colaboración con investigadores/as de University of Padua (10)

2023

  1. New bioisosteric sulphur-containing choline kinase inhibitors with a tracked mode of action

    European journal of medicinal chemistry, Vol. 246, pp. 115003

2022

  1. Biological Evaluation of New Thienopyridinium and Thienopyrimidinium Derivatives as Human Choline Kinase Inhibitors

    Pharmaceutics, Vol. 14, Núm. 4

2021

  1. Anticancer and structure activity relationship of non-symmetrical choline kinase inhibitors

    Pharmaceutics, Vol. 13, Núm. 9

2020

  1. Synthesis, biological evaluation, in silico modeling and crystallization of novel small monocationic molecules with potent antiproliferative activity by dual mechanism

    European Journal of Medicinal Chemistry, Vol. 207

2018

  1. Lead optimization-hit expansion of new asymmetrical pyridinium/quinolinium compounds as choline kinase α1 inhibitors

    Future Medicinal Chemistry, Vol. 10, Núm. 15, pp. 1769-1786

2016

  1. Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1)

    Scientific Reports, Vol. 6

2015

  1. New more polar symmetrical bipyridinic compounds: New strategy for the inhibition of choline kinase α1

    Future Medicinal Chemistry, Vol. 7, Núm. 4, pp. 417-436

2009

  1. WT1 mutations in T-ALL

    Blood, Vol. 114, Núm. 5, pp. 1038-1045

  2. γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

    Nature Medicine, Vol. 15, Núm. 1, pp. 50-58

2007

  1. Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

    Nature Medicine, Vol. 13, Núm. 10, pp. 1203-1210