Publicaciones en colaboración con investigadores/as de Hospital Universitario Virgen del Rocío (23)

2021

  1. Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome

    Nature Communications, Vol. 12, Núm. 1

  2. Human-lineage-specific genomic elements are associated with neurodegenerative disease and APOE transcript usage

    Nature Communications, Vol. 12, Núm. 1

2020

  1. Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information

    Nature Communications, Vol. 11, Núm. 1

2019

  1. Mitochondria function associated genes contribute to Parkinson’s Disease risk and later age at onset

    npj Parkinson's Disease, Vol. 5, Núm. 1

  2. Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability

    npj Parkinson's Disease, Vol. 5, Núm. 1

  3. SNCA and mTOR Pathway Single Nucleotide Polymorphisms Interact to Modulate the Age at Onset of Parkinson's Disease

    Movement Disorders, Vol. 34, Núm. 9, pp. 1333-1344

  4. The Genetic Architecture of Parkinson Disease in Spain: Characterizing Population-Specific Risk, Differential Haplotype Structures, and Providing Etiologic Insight

    Movement Disorders, Vol. 34, Núm. 12, pp. 1851-1863

2018

  1. IMiDs mobilize acute myeloid leukemia blasts to peripheral blood through downregulation of CXCR4 but fail to potentiate AraC/Idarubicin activity in preclinical models of non del5q/5q- AML

    OncoImmunology, Vol. 7, Núm. 9

  2. Intracellular cholesterol accumulation and coenzyme Q10 deficiency in Familial Hypercholesterolemia

    Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1864, Núm. 12, pp. 3697-3713

  3. Molecular characterization of autophagic and apoptotic signaling induced by sorafenib in liver cancer cells

    Journal of Cellular Physiology, Vol. 234, Núm. 1, pp. 692-708

  4. Therapy with coenzyme Q10

    Coenzyme Q10: Uses, Health Effects and Role in Disease (Nova Science Publishers, Inc.), pp. 1-63

2017

  1. Dynamic reorganization of the cytoskeleton during apoptosis: The two coffins hypothesis

    International Journal of Molecular Sciences, Vol. 18, Núm. 11

  2. NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction

    Oncotarget, Vol. 8, Núm. 59, pp. 99740-99756

2016

  1. AMPK as a target in rare diseases

    Current Drug Targets, Vol. 17, Núm. 8, pp. 921-931

2015

  1. Critical role of AMP-activated protein kinase in the balance between mitophagy and mitochondrial biogenesis in MELAS disease

    Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1852, Núm. 11, pp. 2535-2553

  2. Methodology of dietary surveys, studies on nutrition, physical activity and other lifestyles

    Nutricion Hospitalaria, Vol. 31, pp. 9-12

  3. Pharmacological chaperones and coenzyme Q10 treatment improves mutant β-glucocerebrosidase activity and mitochondrial function in neuronopathic forms of gaucher disease

    Scientific Reports, Vol. 5

2013

  1. Apoptotic microtubules delimit an active caspase free area in the cellular cortex during the execution phase of apoptosis

    Cell Death and Disease, Vol. 4, Núm. 3

2012

  1. Recovery of MERRF Fibroblasts and Cybrids Pathophysiology by Coenzyme Q10

    Neurotherapeutics, Vol. 9, Núm. 2, pp. 446-463

  2. Screening of effective pharmacological treatments for MELAS syndrome using yeasts, fibroblasts and cybrid models of the disease

    British Journal of Pharmacology, Vol. 167, Núm. 6, pp. 1311-1328