QUÍMICA FÍSICA
Fachbereich
Johns Hopkins University
Baltimore, Estados UnidosPublikationen in Zusammenarbeit mit Forschern von Johns Hopkins University (20)
2012
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A designed point mutant in fis1 disrupts dimerization and mitochondrial fission
Journal of Molecular Biology, Vol. 423, Núm. 2, pp. 143-158
2010
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Modulation of buried ionizable groups in proteins with engineered surface charge
Journal of the American Chemical Society, Vol. 132, Núm. 4, pp. 1218-1219
2009
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Evidence for conformational heterogeneity of fission protein Fis1 from Saccharomyces cerevisiae
Biochemistry, Vol. 48, Núm. 28, pp. 6598-6609
2002
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Identification and characterization of allophenylnorstatine-based inhibitors of plasmepsin II, an antimalarial target
Biochemistry, Vol. 41, Núm. 7, pp. 2273-2280
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Structural parameterization of the binding enthalpy of small ligands
Proteins: Structure, Function and Genetics, Vol. 49, Núm. 2, pp. 181-190
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The linkage between protein folding and functional cooperativity: Two sides of the same coin?
Annual Review of Biophysics and Biomolecular Structure, Vol. 31, pp. 235-256
2001
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The application of thermodynamic methods in drug design
Thermochimica Acta, Vol. 380, Núm. 2, pp. 217-227
2000
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Development of an isothermal titration microcalorimetric system with digital control and dynamic power Peltier compensation. I. Description and basic performance
Review of Scientific Instruments, Vol. 71, Núm. 4, pp. 1824-1831
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Development of an isothermal titration microcalorimetric system with digital control and dynamic power peltier compensation. II. Characterization and operation mode. Myoglobin adsorption onto polymeric latex particles
Review of Scientific Instruments, Vol. 71, Núm. 4, pp. 1832-1840
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Energetics of the specific binding interaction of the first three zinc fingers of the transcription factor TFIIIA with its cognate DNA sequence
Proteins: Structure, Function and Genetics, Vol. 41, Núm. SUPPL. 4, pp. 50-62
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Thermodynamic basis of resistance to HIV-1 protease inhibition: Calorimetric analysis of the V82F/I84V active site resistant mutant
Biochemistry, Vol. 39, Núm. 39, pp. 11876-11883
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Thermodynamic dissection of the binding energetics of KNI-272, a potent HIV-1 protease inhibitor
Protein Science, Vol. 9, Núm. 9, pp. 1801-1809
1999
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The native state conformational ensemble of the SH3 domain from α- spectrin
Biochemistry, Vol. 38, Núm. 28, pp. 8899-8906
1998
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Molecular basis of resistance to HIV-1 protease inhibition: A plausible hypothesis
Biochemistry, Vol. 37, Núm. 17, pp. 5791-5797
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Structure-based thermodynamic design of peptide ligands: Application to peptide inhibitors of the aspartic protease endothiapepsin
Proteins: Structure, Function and Genetics, Vol. 30, Núm. 1, pp. 74-85
1997
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Structure-based thermodynamic analysis of HIV-1 protease inhibitors
Biochemistry, Vol. 36, Núm. 22, pp. 6588-6596
1996
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Structure-based thermodynamic scale of α-helix propensities in amino acids
Biochemistry, Vol. 35, Núm. 42, pp. 13681-13688
1992
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Temperature and Guanidine Hydrochloride Dependence of the Structural Stability of Ribonuclease T1
Biochemistry, Vol. 31, Núm. 45, pp. 11196-11202
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The Molecular Basis of Cooperativity in Protein Folding. Thermodynamic Dissection of Interdomain Interactions in Phosphoglycerate Kinase
Biochemistry, Vol. 31, Núm. 1, pp. 250-256
1990
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Calorimetrically determined dynamics of complex unfolding transitions in proteins
Annual Review of Biophysics and Biophysical Chemistry, Vol. 19, pp. 159-188