QUÍMICA FÍSICA
DEPARTAMENTO
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Queen's University Belfast
Belfast, Reino UnidoPublicaciones en colaboración con investigadores/as de Queen's University Belfast (7)
2019
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NAD(P)H quinone oxidoreductase (NQO1): An enzyme which needs just enough mobility, in just the right places
Bioscience Reports, Vol. 39, Núm. 1
2018
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Improving the Activity and Stability of Human Galactokinase for Therapeutic and Biotechnological Applications
ChemBioChem, Vol. 19, Núm. 10, pp. 1088-1095
2016
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Conformational dynamics is key to understanding loss-of-function of NQO1 cancer-associated polymorphisms and its correction by pharmacological ligands
Scientific Reports, Vol. 6
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Galactokinase promiscuity: A question of flexibility?
Biochemical Society Transactions, Vol. 44, pp. 116-122
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Natural small molecules as stabilizers and activators of cancer-associated NQO1 polymorphisms
Current Drug Targets, Vol. 17, Núm. 13, pp. 1506-1514
2014
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FAD binding overcomes defects in activity and stability displayed by cancer-associated variants of human NQO1
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1842, Núm. 11, pp. 2163-2173
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The metastability of human UDP-galactose 4′-epimerase (GALE) is increased by variants associated with type III galactosemia but decreased by substrate and cofactor binding
Archives of Biochemistry and Biophysics, Vol. 562, pp. 103-114