Publicaciones en colaboración con investigadores/as de Instituto de Química Médica (21)

2024

  1. Exchangeable Self-Assembled Lanthanide Antennas for PLIM Microscopy

    Angewandte Chemie - International Edition, Vol. 63, Núm. 6

2022

  1. 5-Nitroindazole derivatives as potential therapeutic alternatives against Acanthamoeba castellanii

    Acta Tropica, Vol. 232

  2. A FRET pair for quantitative and superresolution imaging of amyloid fibril formation

    Sensors and Actuators B: Chemical, Vol. 350

  3. Selecting FRET pairs for visualizing amyloid aggregation

    Results in Chemistry, Vol. 4

2020

  1. Environment-Sensitive Probes for Illuminating Amyloid Aggregation in Vitro and in Zebrafish

    ACS Sensors, Vol. 5, Núm. 9, pp. 2792-2799

2019

  1. In vitro assessment of 3-alkoxy-5-nitroindazole-derived ethylamines and related compounds as potential antileishmanial drugs

    Bioorganic Chemistry, Vol. 92

2018

  1. Synthesis and Biological in vitro and in vivo Evaluation of 2-(5-Nitroindazol-1-yl)ethylamines and Related Compounds as Potential Therapeutic Alternatives for Chagas Disease

    ChemMedChem, Vol. 13, Núm. 19, pp. 2104-2118

2017

  1. Simple dialkyl pyrazole-3,5-dicarboxylates show in vitro and in vivo activity against disease-causing trypanosomatids

    Parasitology, Vol. 144, Núm. 9, pp. 1133-1143

2015

  1. Imidazole-containing phthalazine derivatives inhibit Fe-SOD performance in Leishmania species and are active in vitro against visceral and mucosal leishmaniasis

    Parasitology, Vol. 142, Núm. 8, pp. 1115-1129

  2. In vitro leishmanicidal activity of 1,3-disubstituted 5-nitroindazoles

    Acta Tropica, Vol. 148, pp. 170-178

  3. Synthesis and evaluation of in vitro and in vivo trypanocidal properties of a new imidazole-containing nitrophthalazine derivative

    European Journal of Medicinal Chemistry, Vol. 106, pp. 106-119

2014

  1. In vitro leishmanicidal activity of pyrazole-containing polyamine macrocycles which inhibit the Fe-SOD enzyme of Leishmania infantum and Leishmania braziliensis species

    Parasitology, Vol. 141, Núm. 8, pp. 1031-1043

  2. New perspectives on the synthesis and antichagasic activity of 3-alkoxy-1-alkyl-5-nitroindazoles

    European Journal of Medicinal Chemistry, Vol. 74, pp. 124-134

2012

  1. In vitro and in vivo trypanosomicidal activity of pyrazole-containing macrocyclic and macrobicyclic polyamines: Their action on acute and chronic phases of chagas disease

    Journal of Medicinal Chemistry, Vol. 55, Núm. 9, pp. 4231-4243

  2. In vitro leishmanicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against leishmania infantum and leishmania braziliensis species

    Journal of Antimicrobial Chemotherapy, Vol. 67, Núm. 2, pp. 387-397

  3. Phthalazine derivatives containing imidazole rings behave as Fe-SOD inhibitors and show remarkable anti-T. cruzi activity in immunodeficient-mouse mode of infection

    Journal of Medicinal Chemistry, Vol. 55, Núm. 22, pp. 9900-9913

2011

  1. In vivo trypanosomicidal activity of imidazole- or pyrazole-based benzo[ g ]phthalazine derivatives against acute and chronic phases of chagas disease

    Journal of Medicinal Chemistry, Vol. 54, Núm. 4, pp. 970-979

2009

  1. Carbon-carbon weak interactions

    Journal of Physical Chemistry A, Vol. 113, Núm. 29, pp. 8387-8393

2008

  1. Efficient inhibition of iron superoxide dismutase and of Trypanosoma cruzi growth by benzo[g]phthalazine derivatives functionalized with one or two imidazole rings

    Journal of Medicinal Chemistry, Vol. 51, Núm. 6, pp. 1962-1966

2007

  1. 1,4-Bis(alkylamino)benzo[g]phthalazines able to form dinuclear complexes of Cu(II) which as free ligands behave as SOD inhibitors and show efficient in vitro activity against Trypanosoma cruzi

    Bioorganic and Medicinal Chemistry, Vol. 15, Núm. 5, pp. 2081-2091