Publicaciones en las que colabora con ANTONIO ENTRENA GUADIX (90)

2018

  1. Lead optimization-hit expansion of new asymmetrical pyridinium/quinolinium compounds as choline kinase α1 inhibitors

    Future Medicinal Chemistry, Vol. 10, Núm. 15, pp. 1769-1786

2017

  1. Choline kinase inhibition and docking studies of a series of 6-(benzylthio)-9H-purin-9-yl-pyridinium derivatives

    Medicinal Chemistry Research, Vol. 26, Núm. 11, pp. 2809-2815

2016

  1. 1H and 13C NMR spectral assignments of 1,1′-(((ethane-1,2-diylbis(oxy))bis(4,1-phenylene))bis(methylene))-bispyridinium and -bisquinolinium bromide derivatives

    Magnetic Resonance in Chemistry

  2. Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1)

    Scientific Reports, Vol. 6

  3. Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death

    Scientific Reports, Vol. 6

2015

  1. New more polar symmetrical bipyridinic compounds: New strategy for the inhibition of choline kinase α1

    Future Medicinal Chemistry, Vol. 7, Núm. 4, pp. 417-436

  2. New more polar symmetrical choline kinase inhibitors II: Study of setting up a new scaffold for the cancer therapy

    Journal of Biological Research (Italy)

  3. Pharmacophore-Based Virtual Screening to Discover New Active Compounds for Human Choline Kinase α1

    Molecular Informatics, Vol. 34, Núm. 6-7, pp. 458-466

2014

  1. 1H, 13C NMR studies of new 3-aminophenol isomers linked to pyridinium salts

    Magnetic Resonance in Chemistry, Vol. 52, Núm. 1-2, pp. 40-46

  2. Choline kinase active site provides features for designing versatile inhibitors

    Current Topics in Medicinal Chemistry, Vol. 14, Núm. 23, pp. 2684-2693

  3. Discovery of a new binding site on human choline kinase α1: Design, synthesis, crystallographic studies, and biological evaluation of asymmetrical bispyridinium derivatives

    Journal of Medicinal Chemistry, Vol. 57, Núm. 2, pp. 507-515

  4. In vitro antiplasmodial and cytotoxic activities of asymmetrical pyridinium derivatives

    European Journal of Medicinal Chemistry, Vol. 85, pp. 289-292

  5. NMR spectroscopic characterization of new nonsymmetrical bispyridinium choline kinase inhibitors

    Magnetic Resonance in Chemistry

2013

  1. Antiproliferative activity, cell cycle, and apoptosis studies of a series of 6-substituted 9H-purin-9-yl-pyridinium derivatives on a human cervical carcinoma cell line

    ChemMedChem, Vol. 8, Núm. 8, pp. 1266-1269

  2. Determination of potential scaffolds for human choline kinase α1 by chemical deconvolution studies

    ChemBioChem, Vol. 14, Núm. 11, pp. 1291-1295

  3. New non-symmetrical choline kinase inhibitors

    Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 22, pp. 7146-7154

  4. Synthesis and biological evaluation of 4,5-dihydro-1H-pyrazole derivatives as potential nNOS/iNOS selective inhibitors. Part 2: Influence of diverse substituents in both the phenyl moiety and the acyl group

    Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 14, pp. 4132-4142

  5. The mechanism of allosteric coupling in choline kinase α1 revealed by the action of a rationally designed inhibitor

    Angewandte Chemie - International Edition, Vol. 52, Núm. 17, pp. 4582-4586

  6. Unbinding pathways from the glucocorticoid receptor shed light on the reduced sensitivity of glucocorticoid ligands to a naturally occurring, clinically relevant mutant receptor

    Journal of Medicinal Chemistry, Vol. 56, Núm. 17, pp. 7003-7014

2012

  1. 1H and 13C NMR spectral assignments of pyridinium salts linked to a N-9 or N-3 adenine moiety

    Magnetic Resonance in Chemistry, Vol. 50, Núm. 6, pp. 466-469