Publicaciones en las que colabora con ANTONIO ESPINOSA UBEDA (136)

2017

  1. Choline kinase inhibition and docking studies of a series of 6-(benzylthio)-9H-purin-9-yl-pyridinium derivatives

    Medicinal Chemistry Research, Vol. 26, Núm. 11, pp. 2809-2815

2015

  1. Chemical, pharmaceutical and biological information for medicinal products containing chemical and/or biological active substances

    Pharmaceuticals Policy and Law, Vol. 17, Núm. 1-2, pp. 65-79

  2. New more polar symmetrical bipyridinic compounds: New strategy for the inhibition of choline kinase α1

    Future Medicinal Chemistry, Vol. 7, Núm. 4, pp. 417-436

  3. New more polar symmetrical choline kinase inhibitors II: Study of setting up a new scaffold for the cancer therapy

    Journal of Biological Research (Italy)

2014

  1. 1H, 13C NMR studies of new 3-aminophenol isomers linked to pyridinium salts

    Magnetic Resonance in Chemistry, Vol. 52, Núm. 1-2, pp. 40-46

  2. Discovery of a new binding site on human choline kinase α1: Design, synthesis, crystallographic studies, and biological evaluation of asymmetrical bispyridinium derivatives

    Journal of Medicinal Chemistry, Vol. 57, Núm. 2, pp. 507-515

  3. In vitro antiplasmodial and cytotoxic activities of asymmetrical pyridinium derivatives

    European Journal of Medicinal Chemistry, Vol. 85, pp. 289-292

  4. NMR spectroscopic characterization of new nonsymmetrical bispyridinium choline kinase inhibitors

    Magnetic Resonance in Chemistry

2013

  1. Antiproliferative activity, cell cycle, and apoptosis studies of a series of 6-substituted 9H-purin-9-yl-pyridinium derivatives on a human cervical carcinoma cell line

    ChemMedChem, Vol. 8, Núm. 8, pp. 1266-1269

  2. New non-symmetrical choline kinase inhibitors

    Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 22, pp. 7146-7154

  3. The mechanism of allosteric coupling in choline kinase α1 revealed by the action of a rationally designed inhibitor

    Angewandte Chemie - International Edition, Vol. 52, Núm. 17, pp. 4582-4586

2012

  1. 1H and 13C NMR spectral assignments of pyridinium salts linked to a N-9 or N-3 adenine moiety

    Magnetic Resonance in Chemistry, Vol. 50, Núm. 6, pp. 466-469

  2. 1,3,4-Thiadiazole derivatives as selective inhibitors of iNOS versus nNOS: Synthesis and structure-activity dependence

    European Journal of Medicinal Chemistry, Vol. 50, pp. 129-139

  3. Characterization of 4,5-Dihydro-1H-Pyrazole Derivatives by 13C NMR Spectroscopy

    Magnetic Resonance in Chemistry, Vol. 50, Núm. 1, pp. 58-61

  4. Design, synthesis, theoretical calculations and biological evaluation of new non-symmetrical choline kinase inhibitors

    European Journal of Medicinal Chemistry, Vol. 50, pp. 154-162

  5. Melatonin synthetic analogs as nitric oxide synthase inhibitors

    Mini-Reviews in Medicinal Chemistry, Vol. 12, Núm. 7, pp. 600-617

  6. NMR spectroscopic characterization of new 2,3-dihydro-1,3,4-thiadiazole derivatives

    Magnetic Resonance in Chemistry, Vol. 50, Núm. 7, pp. 515-522

2011

  1. Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: A systematic investigation of the influence of linker and cationic heads over affinity and selectivity

    Journal of Medicinal Chemistry, Vol. 54, Núm. 8, pp. 2627-2645

  2. Protective effects of synthetic kynurenines on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice

    Brain Research Bulletin, Vol. 85, Núm. 3-4, pp. 133-140

2010

  1. 2D-QSAR: The Mathematics behind the Drug Design Methodology

    NEW DEVELOPMENTS IN MEDICINAL CHEMISTRY, VOL 1 (BENTHAM SCIENCE PUBL), pp. 79-94