FACULTAD DE FARMACIA
Facultad
Broad Institute
Cambridge, Estados UnidosPublicaciones en colaboración con investigadores/as de Broad Institute (39)
2023
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GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors
American Journal of Psychiatry
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Lung cancer risk discrimination of prediagnostic proteomics measurements compared with existing prediction tools
Journal of the National Cancer Institute, Vol. 115, Núm. 9, pp. 1050-1059
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Schizophrenia risk conferred by rare protein-truncating variants is conserved across diverse human populations
Nature genetics, Vol. 55, Núm. 3, pp. 369-376
2022
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Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
Biological psychiatry, Vol. 91, Núm. 3, pp. 313-327
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Identifying the Common Genetic Basis of Antidepressant Response
Biological Psychiatry Global Open Science, Vol. 2, Núm. 2, pp. 115-126
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Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Nature, Vol. 604, Núm. 7906, pp. 502-508
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Obesity is Associated With Increased Risk of Crohn's disease, but not Ulcerative Colitis: A Pooled Analysis of Five Prospective Cohort Studies
Clinical Gastroenterology and Hepatology, Vol. 20, Núm. 5, pp. 1048-1058
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Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
Biological Psychiatry, Vol. 91, Núm. 1, pp. 102-117
2021
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A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts
Biological Psychiatry, Vol. 90, Núm. 9, pp. 611-620
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Association of polygenic score for major depression with response to lithium in patients with bipolar disorder
Molecular Psychiatry, Vol. 26, Núm. 6, pp. 2457-2470
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Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders
Molecular Psychiatry, Vol. 26, Núm. 4, pp. 1286-1298
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Correction: Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank (Molecular Psychiatry, (2020), 25, 7, (1430-1446), 10.1038/s41380-019-0546-6)
Molecular Psychiatry
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Correction: Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder (Molecular Psychiatry, (2021), 26, 9, (5239-5250), 10.1038/s41380-020-01006-9)
Molecular Psychiatry
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Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Nature genetics, Vol. 53, Núm. 6, pp. 817-829
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Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder
Molecular Psychiatry, Vol. 26, Núm. 9, pp. 5239-5250
2020
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A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank
Nature Communications, Vol. 11, Núm. 1
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Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression
Biological Psychiatry, Vol. 87, Núm. 5, pp. 419-430
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Cumulative Burden of Colorectal Cancer–Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer
Gastroenterology, Vol. 158, Núm. 5, pp. 1274-1286.e12
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Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank
Molecular Psychiatry, Vol. 25, Núm. 7, pp. 1430-1446
2019
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Assessment of bidirectional relationships between physical activity and depression among adults a 2-sample Mendelian randomization study
JAMA Psychiatry, Vol. 76, Núm. 4, pp. 399-408