Publicaciones en colaboración con investigadores/as de University of Edinburgh (143)

2023

  1. Discovery of pyrazolopyrimidines that selectively inhibit CSF-1R kinase by iterative design, synthesis and screening against glioblastoma cells

    RSC Medicinal Chemistry, Vol. 14, Núm. 12, pp. 2611-2624

  2. GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors

    American Journal of Psychiatry

  3. In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys: Overcoming Intracellular Deactivation

    Nano Letters, Vol. 23, Núm. 3, pp. 804-811

  4. Polygenic risk prediction: why and when out-of-sample prediction R2 can exceed SNP-based heritability

    American Journal of Human Genetics, Vol. 110, Núm. 7, pp. 1207-1215

2022

  1. A 5-FU Precursor Designed to Evade Anabolic and Catabolic Drug Pathways and Activated by Pd Chemistry in Vitro and in Vivo

    Journal of Medicinal Chemistry, Vol. 65, Núm. 1, pp. 552-561

  2. A multicomponent reaction platform towards multimodal near-infrared BODIPY dyes for STED and fluorescence lifetime imaging

    RSC Chemical Biology, Vol. 3, Núm. 10, pp. 1251-1259

  3. Associations of BMI with COVID-19 vaccine uptake, vaccine effectiveness, and risk of severe COVID-19 outcomes after vaccination in England: a population-based cohort study

    The Lancet Diabetes and Endocrinology, Vol. 10, Núm. 8, pp. 571-580

  4. Bacterial and fungal communities in tracheal aspirates of intubated COVID-19 patients: a pilot study

    Scientific Reports, Vol. 12, Núm. 1

  5. Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

    Biological psychiatry, Vol. 91, Núm. 3, pp. 313-327

  6. EZH2 endorses cell plasticity to non-small cell lung cancer cells facilitating mesenchymal to epithelial transition and tumour colonization

    Oncogene, Vol. 41, Núm. 28, pp. 3611-3624

  7. Identifying the Common Genetic Basis of Antidepressant Response

    Biological Psychiatry Global Open Science, Vol. 2, Núm. 2, pp. 115-126

  8. Mapping genomic loci implicates genes and synaptic biology in schizophrenia

    Nature, Vol. 604, Núm. 7906, pp. 502-508

  9. Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells

    Molecular Cell, Vol. 82, Núm. 23, pp. 4537-4547.e7

  10. Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

    Biological Psychiatry, Vol. 91, Núm. 1, pp. 102-117

  11. Small Molecule Kinase Inhibitor Drugs (1995–2021): Medical Indication, Pharmacology, and Synthesis

    Journal of Medicinal Chemistry, Vol. 65, Núm. 2, pp. 1047-1131

  12. Truly-Biocompatible Gold Catalysis Enables Vivo-Orthogonal Intra-CNS Release of Anxiolytics

    Angewandte Chemie - International Edition, Vol. 61, Núm. 1

2021

  1. A conformation selective mode of inhibiting SRC improves drug efficacy and tolerability

    Cancer Research, Vol. 81, Núm. 21, pp. 5438-5450

  2. A minimally-masked inactive prodrug of panobinostat that is bioorthogonally activated by gold chemistry

    Bioorganic and Medicinal Chemistry, Vol. 41

  3. Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

    Molecular Psychiatry, Vol. 26, Núm. 6, pp. 2457-2470

  4. Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

    Molecular Psychiatry, Vol. 26, Núm. 4, pp. 1286-1298