FACULTAD DE MEDICINA
Facultad
Instituto de Química Médica
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Instituto de Química Médica (13)
2022
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Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors
Journal of medicinal chemistry, Vol. 65, Núm. 20, pp. 13660-13680
2020
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Environment-Sensitive Probes for Illuminating Amyloid Aggregation in Vitro and in Zebrafish
ACS Sensors, Vol. 5, Núm. 9, pp. 2792-2799
2018
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The Melatonin Analog IQM316 May Induce Adult Hippocampal Neurogenesis and Preserve Recognition Memories in Mice
Cell Transplantation, Vol. 27, Núm. 3, pp. 423-437
2015
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Fluorination effects on NOS inhibitory activity of pyrazoles related to curcumin
Molecules, Vol. 20, Núm. 9, pp. 15643-15665
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Synthesis, structure and biological activity of 3(5)-trifluoromethyl-1H-pyrazoles derived from hemicurcuminoids
Journal of Molecular Structure, Vol. 1100, pp. 518-529
2012
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In vitro and in vivo trypanosomicidal activity of pyrazole-containing macrocyclic and macrobicyclic polyamines: Their action on acute and chronic phases of chagas disease
Journal of Medicinal Chemistry, Vol. 55, Núm. 9, pp. 4231-4243
2011
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In vivo trypanosomicidal activity of imidazole- or pyrazole-based benzo[ g ]phthalazine derivatives against acute and chronic phases of chagas disease
Journal of Medicinal Chemistry, Vol. 54, Núm. 4, pp. 970-979
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Synthesis and biological evaluation of indazole derivatives
European Journal of Medicinal Chemistry, Vol. 46, Núm. 4, pp. 1439-1447
2009
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Fluorinated indazoles as novel selective inhibitors of nitric oxide synthase (NOS): Synthesis and biological evaluation
Bioorganic and Medicinal Chemistry, Vol. 17, Núm. 17, pp. 6180-6187
2008
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Efficient inhibition of iron superoxide dismutase and of Trypanosoma cruzi growth by benzo[g]phthalazine derivatives functionalized with one or two imidazole rings
Journal of Medicinal Chemistry, Vol. 51, Núm. 6, pp. 1962-1966
2007
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1,4-Bis(alkylamino)benzo[g]phthalazines able to form dinuclear complexes of Cu(II) which as free ligands behave as SOD inhibitors and show efficient in vitro activity against Trypanosoma cruzi
Bioorganic and Medicinal Chemistry, Vol. 15, Núm. 5, pp. 2081-2091
1990
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Pyridinium azolate betaines and their derivatives: a new class of antiprotozoal agents
European Journal of Medicinal Chemistry, Vol. 25, Núm. 4, pp. 309-319
1987
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Activity against Trypanosoma cruzi of New Analogues of Nifurtimox
Archiv der Pharmazie, Vol. 320, Núm. 2, pp. 115-120