Caracterización histológica en uretroplastias experimentales de mucosa oral
- Martín Cano, F.
- Marañés Gálvez, C.
- Liceras Liceras, E.
- García Gómez, M.
- Díaz Moreno, E.
- Ruiz Montes, A. M.
- Garzón Bello, Ingrid
- Fernández Valadés, Ricardo
ISSN: 0365-7965
Any de publicació: 2010
Tom: 95
Número: 781
Pàgines: 5-9
Tipus: Article
Altres publicacions en: Actualidad médica
Resum
Introduction: Several surgical techniques have been used for urethral reconstruction. In this context, oral mucosa grafts are currently required. The aim of this study was to analyze the structural and ultraestructural modifications of grafted tissues exposed to different environmental conditions. Material and methods: 20 male Wistar rats under general anesthesia were used. Control group was set, and groups of study were set, and underwent an urethroplasty with oral mucosa graft analyzed at 7, 14 and 30 days. Results: The technique used was feasible. The analysis in oral grafted tissues showed an adequate integration level, with a shrinking interphase formation between the oral and urethral mucosa. At 30 days, the integration was completed and the oral mucosa showed 5-6 flat cell layers, with a similar structure to the urethral epithelium. Conclusions: The oral mucosa used as heterologous graft was able to differentiate in an adequate way to generate a structurally similar tissue to the native urethra.