Nanopartículas Magnéticas en el Diagnóstico y Tratamiento del Cáncer

  1. Doello, Kevin 1
  2. Cabeza, Laura 1
  3. Ortiz, Raul 2
  4. Arias, Jose Luis 1
  5. Melguizo, Consolación 1
  6. Prados, Jose 1
  1. 1 Universidad de Granada
    info

    Universidad de Granada

    Granada, España

    ROR https://ror.org/04njjy449

  2. 2 Universidad de Jaén
    info

    Universidad de Jaén

    Jaén, España

    ROR https://ror.org/0122p5f64

Journal:
Actualidad médica

ISSN: 0365-7965

Year of publication: 2015

Tome: 100

Issue: 796

Pages: 139-145

Type: Article

DOI: 10.15568/AM.2015.796.RE01 DIALNET GOOGLE SCHOLAR lock_openDIGIBUG editor

More publications in: Actualidad médica

Sustainable development goals

Abstract

The advances in the field of nanotechnology include the development of new nanoparticles that are being used inside oncology, not only as new drugs transporters that are able to direct them to specific locations at the same time decreasing their systemic effects, furthermore, they generate localized heat (hyperthermia) as an antitumor therapy and for the localization and visualization of this type of pathology. In this context, nanoparticles with magnetic cores that have paramagnetic properties are gaining importance in the field of tumor diagnosis and also in the treatment, either only for applying hyperthermia phenomena or to combine them with targeting phenomenom of cytotoxic drugs by the addition of molecules onto the nanoparticle surface that recognize some kind of cancer biomarker (active targeting). The main objective of this review is to show the most relevant advances in the development of nanoplatforms that have magnetic cores and are a new strategy for the cancer treatment and/or diagnosis (theragnosis) by the mention of the main in vitro and in vivo assays, specially the clinical trials most important of this new therapeutic concept inside within the field of oncology.

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