La terapia de desbridamiento larval en heridas crónicasuna revisión de revisiones

  1. Andrés Redondo Tébar 1
  2. Salvador Postigo Mota 2
  1. 1 Universidad de Castilla-La Mancha
    info

    Universidad de Castilla-La Mancha

    Ciudad Real, España

    ROR https://ror.org/05r78ng12

  2. 2 Universidad de Extremadura
    info

    Universidad de Extremadura

    Badajoz, España

    ROR https://ror.org/0174shg90

Journal:
Revista ROL de enfermería

ISSN: 0210-5020

Year of publication: 2022

Issue Title: Heridas y otras lesiones cutáneas

Volume: 45

Issue: 2

Pages: 42-57

Type: Article

More publications in: Revista ROL de enfermería

Abstract

Chronic wounds are a worldwide health problem which affects between 1-2% of the population with potential negative implications for the patient and may even lead to limb amputation as well as death. Tissue management is the first step in preparing the wound bed, debriding devitalised tissue, reducing the risk of infection, controlling exudate, and stimulating the growth of granulation tissue, which together contribute to wound healing. Among the different types of debridement, we find the maggot debridement therapy (MDT) which has been used with varying priority since ancient times. Nowadays, MDT has received renewed interest due to its benefits in the treatment of chronic wounds, which are mainly: rapid and effective debridement, infection and biofilm control, and wound healing. The aim of the study was to provide information related to the use of larval therapy in chronic wounds, to report the current evidence on the application of the treatment and to be able, in this way, to introduce larval therapy from a historical, theoretical, and practical perspective.

Bibliographic References

  • Armstrong DG, Meyr AJ. Basic principles of wound healing. Published 2021. Accessed July 2, 2021. https://www.uptodate.com/contents/basic-principles-of-wound-healing?search=chronic wound definition&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1
  • Baranoski S, Ayello E, Niezgoda J, Langemo D. Wound Assessment. In: Wound Care Essentials: Practice Principles. 5th ed. Wolters Kluwer; 2020.
  • Armstrong DG, Meyr AJ. Risk factors for impaired wound healing and wound complications. Published 2021. https://www.uptodate.com/contents/risk-factors-for-impaired-wound-healing-and-wound-complications#H3845567735
  • Zubir MZM, Holloway S, Noor NM, Mohd Zubir MZ, Holloway S, Mohd Noor N. Maggot Therapy in Wound Healing: A Systematic Review. Int J Environ Res Public Health. 2020;17(17):6103. doi:10.3390/ijerph17176103
  • Nussbaum SR, Carter MJ, Fife CE, et al. An Economic Evaluation of the Impact, Cost, and Medicare Policy Implications of Chronic Nonhealing Wounds. Value Heal. 2018;21(1):27-32. doi:10.1016/j.jval.2017.07.007
  • Woo K, Walters N, de Gouveia Santos V. Quality of Life and Ethical Issues. In: Wound Care Essentials: Practice Principles. Wolters Kluwer; 2020.
  • Hurd T. Understanding the financial benefits of optimising wellbeing in patients living with a wound. Wounds Int J. 2013;4(2):13-17.
  • Raposio E, Bortolini S, Maistrello L, Grasso DA. Larval Therapy for Chronic Cutaneous Ulcers: Historical Review and Future Perspectives. Wounds a Compend Clin Res Pract. 2017;29(12):367-373. http://www.ncbi.nlm.nih.gov/pubmed/29324424
  • Martinengo L, Olsson M, Bajpai R, et al. Prevalence of chronic wounds in the general population: systematic review and meta-analysis of observational studies. Ann Epidemiol. 2019;29:8-15. doi:10.1016/j.annepidem.2018.10.005
  • European Wound Management Association (EWMA). Position Document: Wound Bed Preparation in Practice.; 2004. https://ewma.org/fileadmin/user_upload/EWMA.org/Position_documents_2002-2008/pos_doc_English_final_04.pdf
  • Moya-López J, Costela-Ruiz V, García-Recio E, Sherman RA, De Luna-Bertos E. Advantages of Maggot Debridement Therapy for Chronic Wounds: A Bibliographic Review. Adv Skin Wound Care. 2020;33(10):515-525. doi:10.1097/01.ASW.0000695776.26946.68
  • Sibbald R, Niezgoda J, Ayello E. Wound Debridement. In: Wound Care Essentials: Practice Principles. Wolters Kluwer; 2020.
  • Jordan A, Khiyani N, Bowers S, Lukaszczyk J, Stawicki S. Maggot debridement therapy: A practical review. Int J Acad Med. 2018;4(1):21. doi:10.4103/IJAM.IJAM_6_18
  • Sherman RA, Hall MJRR, Thomas S. Medicinal Maggots: An Ancient Remedy for Some Contemporary Afflictions. Annu Rev Entomol. 2000;45(1):55-81. doi:10.1146/annurev.ento.45.1.55
  • Fleischmann W, Grassberger M, Sherman R. Maggot Therapy : A Handbook of Maggot-Assisted Wound Healing. Published online 2004. http://dx.doi.org/10.1055/b-002-54063
  • Baer WS. The Classic: The Treatment of Chronic Osteomyelitis With the Maggot (Larva of the Blow Fly). Clin Orthop Relat Res. 2011;469(4):920-944. doi:10.1007/s11999-010-1416-3
  • Davydov L. Maggot Therapy in Wound Management in Modern Era and a Review of Published Literature. J Pharm Pract. 2011;24(1):89-93. doi:10.1177/0897190010366938
  • Food & Drugs Administration. Capsular Decisions – Products Assigned to CDRH. Published 2021. Accessed July 15, 2021. https://www.fda.gov/combination-products/rfd-jurisdictional-decisions/capsular-decisions-products-assigned-cdrh
  • Naik G, Harding K. Maggot debridement therapy: the current perspectives. Chronic Wound Care Manag Res. 2017;Volume 4:121-128. doi:10.2147/CWCMR.S117271
  • International Biotherapy Society. Maggot Debridement Therapy (MDT). Published 2021. Accessed July 15, 2021. http://biotherapysociety.org/maggot-debridement-therapy-mdt/
  • Abela G. Benefits of maggot debridement therapy on leg ulcers: A literature review. Br J Community Nurs. 2017;22(June):S14-S19. doi:10.12968/bjcn.2017.22.Sup6.S14
  • Bazaliński D, Kózka M, Karnas M, Więch P. Effectiveness of Chronic Wound Debridement with the Use of Larvae of Lucilia Sericata. J Clin Med. 2019;8(11):1845. doi:10.3390/jcm8111845
  • King C. Changing attitudes toward maggot debridement therapy in wound treatment: A review and discussion. J Wound Care. 2020;29(2):S28-S34. doi:10.12968/jowc.2020.29.Sup2c.S28
  • Nigam Y, Morgan C. Does maggot therapy promote wound healing? The clinical and cellular evidence. J Eur Acad Dermatology Venereol. 2016;30(5):776-782. doi:10.1111/jdv.13534
  • Shi E, Shofler D. Maggot debridement therapy: a systematic review. Br J Community Nurs. 2014;19(Sup12):S6-S13. doi:10.12968/bjcn.2014.19.Sup12.S6
  • Sun X, Jiang K, Chen J, et al. A systematic review of maggot debridement therapy for chronically infected wounds and ulcers. Int J Infect Dis. 2014;25:32-37. doi:10.1016/j.ijid.2014.03.1397
  • Zarchi K, Jemec GB. The efficacy of maggot debridement therapy – a review of comparative clinical trials. Int Wound J. 2012;9(5):469-477. doi:10.1111/j.1742-481X.2011.00919.x
  • Sherman RA. Mechanisms of maggot-induced wound healing: What do we know, and where do we go from here? Evidence-based Complement Altern Med. 2014;2014. doi:10.1155/2014/592419
  • García IG, Polina S. Revisión sistemática de evidencia científica. Rev Int Ciencias Podol. 2009;3(1).
  • Ballester Martínez L, Martínez Monleon E, Serra Perucho N, Palomar Llatas F. Utilización de la terapia larval en heridas desvitalizadas. Revisión bibliográfica. Enfermería Dermatológica. Published online 2016:27-33.
  • Perez Jaimes GA, Rueda Barrera WJ, Rueda Díaz LJ. Topical Products for the Protection of Periwound Skin: A Scoping Review. Wounds a Compend Clin Res Pract. Published online June 7, 2020. http://www.ncbi.nlm.nih.gov/pubmed/32813670
  • National Health Service – NHS. Pathway for Larval Debridement Therapy.; 2021. https://www.rdash.nhs.uk/wp-content/uploads/2019/07/TVWCM-v1-Appx-12-Larval-Debridement-Therapy.pdf
  • Sherman RA. Maggot Therapy for Foot and Leg Wounds. Int J Low Extrem Wounds. 2002;1(2):135-142. doi:10.1177/1534734602001002009
  • Steenvoorde P, Jacobi CE, Oskam J. Maggot Debridement Therapy. Adv Skin Wound Care. 2005;18(8):430-435. doi:10.1097/00129334-200510000-00010
  • Sherman RA. What the Studies Say: Contained and Free-Range Maggot Therapy Delivery. Published 2015. Accessed July 15, 2021. https://www.woundsource.com/blog/what-studies-say-contained-and-free-range-maggot-therapy-delivery
  • Sherman RA. Bagged and Free-Range: How Different Maggot Therapy Dressings Work. Published 2015. Accessed July 15, 2021. https://www.woundsource.com/blog/bagged-and-free-range-how-different-maggot-therapy-dressings-work
  • Sherman RA. When Should Contained Maggot Therapy Be Used for Wound Debridement? Published 2016. Accessed July 15, 2021. https://www.woundsource.com/blog/when-should-contained-maggot-therapy-used-wound-debridement
  • Sibbald RG, Elliott JA, Persaud-Jaimangal R, et al. Wound Bed Preparation 2021. Adv Skin Wound Care. 2021;34(4):183-195. doi:10.1097/01.ASW.0000733724.87630.d6
  • Cleveland Museum of Natural History. Life cycle of the black blow fly. Accessed July 15, 2021. https://www.nlm.nih.gov/exhibition/visibleproofs/galleries/technologies/blowfly.html
  • Cazander G, Pritchard DI, Nigam Y, Jung W, Nibbering PH. Multiple actions of Lucilia sericata larvae in hard-to-heal wounds. BioEssays. 2013;35(12):1083-1092. doi:10.1002/bies.201300071
  • Yan L, Chu J, Li M, et al. Pharmacological Properties of the Medical Maggot: A Novel Therapy Overview. Evidence-based Complement Altern Med. 2018;2018. doi:10.1155/2018/4934890