QUIMBIO-F
QUÍMICA BIOLÓGICA APLICADA: NUEVOS FÁRMACOS Y BIORREMEDIACIÓN
Publicaciones (40) Publicaciones en las que ha participado algún/a investigador/a
2023
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Cytotoxic evaluation of YSL-109 in a triple negative breast cancer cell line and toxicological evaluations
Naunyn-Schmiedeberg's Archives of Pharmacology, Vol. 396, Núm. 6, pp. 1211-1222
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New amidine-benzenesulfonamides as iNOS inhibitors for the therapy of the triple negative breast cancer
European Journal of Medicinal Chemistry, Vol. 248
2022
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Bioactive imidamide-based compounds targeted against nitric oxide synthase
Bioorganic Chemistry, Vol. 120
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Effectiveness of an O-Alkyl Hydroxamate in Dogs with Naturally Acquired Canine Leishmaniosis: An Exploratory Clinical Trial
Animals, Vol. 12, Núm. 19
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In silico design of HDAC6 inhibitors with neuroprotective effects
Journal of Biomolecular Structure and Dynamics, Vol. 40, Núm. 24, pp. 14204-14222
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Lactate dehydrogenase A inhibitors with a 2,8-dioxabicyclo[3.3.1]nonane scaffold: A contribution to molecular therapies for primary hyperoxalurias
Bioorganic Chemistry, Vol. 129
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New salicylic acid derivatives, double inhibitors of glycolate oxidase and lactate dehydrogenase, as effective agents decreasing oxalate production
European Journal of Medicinal Chemistry, Vol. 237
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Targeting Several Biologically Reported Targets of Glioblastoma Multiforme by Assaying 2D and 3D Cultured Cells
Cellular and Molecular Neurobiology, Vol. 42, Núm. 6, pp. 1909-1920
2021
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Insights into the co-assemblies formed by different aromatic short-peptide amphiphiles
Polymer Chemistry, Vol. 12, Núm. 47, pp. 6832-6845
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Modifications on the tetrahydroquinoline scaffold targeting a phenylalanine cluster on GPER as antiproliferative compounds against renal, liver and pancreatic cancer cells
Pharmaceuticals, Vol. 14, Núm. 1, pp. 1-19
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Small molecule-based enzyme inhibitors in the treatment of primary hyperoxalurias
Journal of Personalized Medicine, Vol. 11, Núm. 2, pp. 1-31
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Synthesis, bioevaluation and docking studies of new imidamide derivatives as nitric oxide synthase inhibitors
Bioorganic and Medicinal Chemistry, Vol. 44
2020
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Hydroxamic acid derivatives as HDAC1, HDAC6 and HDAC8 inhibitors with antiproliferative activity in cancer cell lines
Scientific Reports, Vol. 10, Núm. 1
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NMR studies of pyrimidinic nucleosides derived from 2,3-dideoxy-d-ribose with inhibitory activity on LINE-1 mobility
Magnetic Resonance in Chemistry
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O-Alkyl Hydroxamates Display Potent and Selective Antileishmanial Activity
Journal of Medicinal Chemistry, Vol. 63, Núm. 11, pp. 5734-5751
2019
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A nanodelivered Vorinostat derivative is a promising oral compound for the treatment of visceral leishmaniasis
Pharmacological Research, Vol. 139, pp. 375-383
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Investigation of the stereochemical-dependent DNA and RNA binding of arginine-based nucleopeptides
Symmetry, Vol. 11, Núm. 4
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Synthesis and Characterization of Specific Reverse Transcriptase Inhibitors for Mammalian LINE-1 Retrotransposons
Cell Chemical Biology, Vol. 26, Núm. 8, pp. 1095-1109.e14
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Synthesis and Characterization of a Click-Assembled 18-Atom Macrocycle That Displays Selective AXL Kinase Inhibitory Activity
ACS Omega, Vol. 4, Núm. 25, pp. 21620-21626