Publikationen in Zusammenarbeit mit Forschern von University of Ferrara (36)

2014

  1. Synthesis and biological evaluation of novel 2-amino-3-aroyl-4-neopentyl-5- substituted thiophene derivatives as allosteric enhancers of the A1 adenosine receptor

    Bioorganic and Medicinal Chemistry, Vol. 22, Núm. 1, pp. 148-166

2013

  1. Synthesis and biological effects of novel 2-amino-3-(4-chlorobenzoyl)-4- substituted thiophenes as allosteric enhancers of the A1 adenosine receptor

    European Journal of Medicinal Chemistry, Vol. 67, pp. 409-427

2012

  1. Structure-activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1- yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A 1 adenosine receptor

    Bioorganic and Medicinal Chemistry, Vol. 20, Núm. 2, pp. 996-1007

  2. Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor

    Journal of Medicinal Chemistry, Vol. 55, Núm. 17, pp. 7719-7735

2011

  1. Synthesis and Antitumor Molecular Mechanism of Agents Based on Amino 2-(3',4',5'-Trimethoxybenzoyl)benzo[b]furan: Inhibition of Tubulin and Induction of Apoptosis

    ChemMedChem, Vol. 6, Núm. 10, pp. 1841-1853

2010

  1. Substituted 2-(3′,4′,5′-trimethoxybenzoyl)-benzo[b] thiophene derivatives as potent tubulin polymerization inhibitors

    Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 14, pp. 5114-5122

  2. Symmetrical α-bromoacryloylamido diaryldienone derivatives as a novel series of antiproliferative agents. Design, synthesis and biological evaluation

    Bioorganic and Medicinal Chemistry Letters, Vol. 20, Núm. 9, pp. 2733-2739

  3. Synthesis and antitumor activity of 1,5-disubstituted 1,2,4-triazoles as cis-restricted combretastatin analogues

    Journal of Medicinal Chemistry, Vol. 53, Núm. 10, pp. 4248-4258

  4. Synthesis and evaluation of haloacetyl, α-bromoacryloyl and nitrooxyacetyl benzo[b]furan and benzo[b]thiophene derivatives as potent antiproliferative agents against leukemia l1210 and K562 cells

    Letters in Drug Design and Discovery, Vol. 7, Núm. 7, pp. 476-486

2009

  1. 2-Arylamino-4-amino-5-aroylthiazoles. "One-pot" synthesis and biological evaluation of a new class of inhibitors of tubulin polymerization

    Journal of Medicinal Chemistry, Vol. 52, Núm. 17, pp. 5551-5555

  2. Design, synthesis and structure-activity relationship of 2-(3′,4′,5′-trimethoxybenzoyl)-benzo[b]furan derivatives as a novel class of inhibitors of tubulin polymerization

    Bioorganic and Medicinal Chemistry, Vol. 17, Núm. 19, pp. 6862-6871

  3. Discovery of 8-methoxypyrazino[1,2-a]indole as a new potent antiproliferative agent against human leukemia K562 cells. A structure-activity relationship study

    Letters in Drug Design and Discovery, Vol. 6, Núm. 4, pp. 298-303

  4. Hybrid α-bromoacryloylamido chalcones. Design, synthesis and biological evaluation

    Bioorganic and Medicinal Chemistry Letters, Vol. 19, Núm. 7, pp. 2022-2028

2008

  1. Design, synthesis, and biological evaluation of thiophene analogues of chalcones

    Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 10, pp. 5367-5376

  2. Synthesis and biological evaluation of 1-methyl-2-(3′,4′, 5′-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors

    Journal of Medicinal Chemistry, Vol. 51, Núm. 5, pp. 1464-1468

  3. Synthesis and biological evaluation of 2-(3′,4′,5′-trimethoxybenzoyl)-3-N,N-dimethylamino benzo[b]furan derivatives as inhibitors of tubulin polymerization

    Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 18, pp. 8419-8426

  4. Synthesis and biological evaluation of 2-amino-3-(3′,4′,5′-trimethoxybenzoyl)-6-substituted-4 ,5,6,7-tetrahydrothieno[2,3-c]pyridine derivatives as antimitotic agents and inhibitors of tubulin polymerization

    Bioorganic and Medicinal Chemistry Letters, Vol. 18, Núm. 18, pp. 5041-5045

  5. Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N- (substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor

    Journal of Medicinal Chemistry, Vol. 51, Núm. 18, pp. 5875-5879

  6. Synthesis and biological evaluation of 2-aroyl-4-phenyl-5-hydroxybenzofurans as a new class of antitubulin agents

    Medicinal Chemistry, Vol. 4, Núm. 6, pp. 558-564

  7. Synthesis and biological evaluation of a series of 2-(3,4,5- trimethoxybenzoyl)-indol-3-yl acetic acid derivatives as potential agents against human leukemia K562 cells

    Letters in Drug Design and Discovery, Vol. 5, Núm. 3, pp. 214-220