Publicaciones (71) Publicaciones de ENRIQUE JOSÉ COBOS DEL MORAL

2024

  1. Adults with excess weight or obesity, but not with overweight, report greater pain intensities than individuals with normal weight: a systematic review and meta-analysis

    Frontiers in Endocrinology, Vol. 15

2023

  1. Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity

    Journal of Medicinal Chemistry, Vol. 66, Núm. 16, pp. 11447-11463

  2. Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain

    Journal of Medicinal Chemistry, Vol. 66, Núm. 14, pp. 9658-9683

  3. Minocycline Prevents the Development of Key Features of Inflammation and Pain in DSS-induced Colitis in Mice

    Journal of Pain, Vol. 24, Núm. 2, pp. 304-319

  4. Peer review of teaching: using the nominal group technique to improve a program in a university setting with no previous experience

    International Journal for Academic Development, Vol. 28, Núm. 4, pp. 385-397

  5. Sigma-1 receptor agonism exacerbates immune-driven nociception: Role of TRPV1 + nociceptors

    Biomedicine and Pharmacotherapy, Vol. 167

  6. Small Synthetic Hyaluronan Disaccharide BIS014 Mitigates Neuropathic Pain in Mice

    Journal of Pain, Vol. 24, Núm. 1, pp. 68-83

  7. Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands

    ACS Chemical Neuroscience, Vol. 14, Núm. 10, pp. 1845-1858

  8. The sigma-1 receptor curtails endogenous opioid analgesia during sensitization of TRPV1 nociceptors

    British Journal of Pharmacology, Vol. 180, Núm. 8, pp. 1148-1167

2022

  1. Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: Design, synthesis, and pharmacological evaluation

    European Journal of Medicinal Chemistry, Vol. 230

  2. Soluble Epoxide Hydrolase Inhibitors: Design, Synthesis, in vitro Profiling and in vivo Evaluation in Murine Models of Pain

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 36

  3. Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties

    ACS Chemical Neuroscience, Vol. 13, Núm. 1, pp. 1-15

  4. Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors

    Journal of medicinal chemistry, Vol. 65, Núm. 20, pp. 13660-13680

2021

  1. Calmodulin supports trpa1 channel association with opioid receptors and glutamate nmda receptors in the nervous tissue

    International Journal of Molecular Sciences, Vol. 22, Núm. 1, pp. 1-21

  2. El sistema opioide endógeno periférico participa en el efecto antinociceptivo de la pregabalina

    Encuentros en Neurociencias (Universidad de Granada), pp. 161-188

  3. Sigma-1 receptor: A drug target for the modulation of neuroimmune and neuroglial interactions during chronic pain

    Pharmacological Research, Vol. 163

  4. Tricyclic Triazoles as σ1Receptor Antagonists for Treating Pain

    Journal of Medicinal Chemistry, Vol. 64, Núm. 8, pp. 5157-5170

2020

  1. Dimethyl fumarate: From an antipsoriatic drug to a promising antineuropathic drug

    Revista de la Sociedad Espanola del Dolor

  2. Editorial: Sigma Receptors

    Frontiers in Pharmacology

  3. El receptor sigma-1: una diana farmacológica que modula las interacciones neuroinmunitarias y neurogliales durante el dolor crónico

    Actualidad en farmacología y terapéutica, Vol. 18, Núm. 3, pp. 173-186