Publicacions (75) Publicacions de ENRIQUE JOSÉ COBOS DEL MORAL

2024

  1. Adults with excess weight or obesity, but not with overweight, report greater pain intensities than individuals with normal weight: a systematic review and meta-analysis

    Frontiers in Endocrinology, Vol. 15

  2. Pharmacological differences in postoperative cutaneous sensitivity, pain at rest, and movement-induced pain in laparotomized mice

    Biomedicine and Pharmacotherapy, Vol. 180

  3. Sigma-1 Receptors Control Neuropathic Pain and Peripheral Neuroinflammation After Nerve Injury in Female Mice: A Transcriptomic Study

    Journal of Neuroimmune Pharmacology, Vol. 19, Núm. 1

  4. The proof of concept of 2-{3-[N-(1-benzylpiperidin-4-yl)propyl]amino}-6-[N-methyl-N-(prop-2-yn-1-yl)amino]-4-phenylpyridine-3,5-dicarbonitrile for the therapy of neuropathic pain

    Bioorganic Chemistry, Vol. 150

  5. The role of neutrophils in pain: systematic review and meta-analysis of animal studies

    Pain

2023

  1. Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity

    Journal of Medicinal Chemistry, Vol. 66, Núm. 16, pp. 11447-11463

  2. Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain

    Journal of Medicinal Chemistry, Vol. 66, Núm. 14, pp. 9658-9683

  3. Minocycline Prevents the Development of Key Features of Inflammation and Pain in DSS-induced Colitis in Mice

    Journal of Pain, Vol. 24, Núm. 2, pp. 304-319

  4. Peer review of teaching: using the nominal group technique to improve a program in a university setting with no previous experience

    International Journal for Academic Development, Vol. 28, Núm. 4, pp. 385-397

  5. Sigma-1 receptor agonism exacerbates immune-driven nociception: Role of TRPV1 + nociceptors

    Biomedicine and Pharmacotherapy, Vol. 167

  6. Small Synthetic Hyaluronan Disaccharide BIS014 Mitigates Neuropathic Pain in Mice

    Journal of Pain, Vol. 24, Núm. 1, pp. 68-83

  7. Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands

    ACS Chemical Neuroscience, Vol. 14, Núm. 10, pp. 1845-1858

  8. The sigma-1 receptor curtails endogenous opioid analgesia during sensitization of TRPV1 nociceptors

    British Journal of Pharmacology, Vol. 180, Núm. 8, pp. 1148-1167

2022

  1. Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: Design, synthesis, and pharmacological evaluation

    European Journal of Medicinal Chemistry, Vol. 230

  2. Soluble Epoxide Hydrolase Inhibitors: Design, Synthesis, in vitro Profiling and in vivo Evaluation in Murine Models of Pain

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 36

  3. Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties

    ACS Chemical Neuroscience, Vol. 13, Núm. 1, pp. 1-15

  4. Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors

    Journal of medicinal chemistry, Vol. 65, Núm. 20, pp. 13660-13680

2021

  1. Calmodulin supports trpa1 channel association with opioid receptors and glutamate nmda receptors in the nervous tissue

    International Journal of Molecular Sciences, Vol. 22, Núm. 1, pp. 1-21

  2. El sistema opioide endógeno periférico participa en el efecto antinociceptivo de la pregabalina

    Encuentros en Neurociencias (Universidad de Granada), pp. 161-188

  3. Sigma-1 receptor: A drug target for the modulation of neuroimmune and neuroglial interactions during chronic pain

    Pharmacological Research, Vol. 163