Publications (36) FRANCISCO RAFAEL NIETO LÓPEZ publications

2023

  1. Conformationally Restricted σ1 Receptor Antagonists from (−)-Isopulegol

    Journal of Medicinal Chemistry, Vol. 66, Núm. 7, pp. 4999-5020

  2. Efficacy and Security of Tetrodotoxin in the Treatment of Cancer-Related Pain: Systematic Review and Meta-Analysis

    Marine Drugs, Vol. 21, Núm. 5

2022

  1. Synthesis of tropane-based σ1 receptor antagonists with antiallodynic activity

    European Journal of Medicinal Chemistry, Vol. 230

2021

  1. Chemoenzymatic synthesis of 2,6-disubstituted tetrahydropyrans with high σ1 receptor affinity, antitumor and analgesic activity

    European Journal of Medicinal Chemistry, Vol. 219

  2. Discovery of a σ1 receptor antagonist by combination of unbiased cell painting and thermal proteome profiling

    Cell Chemical Biology, Vol. 28, Núm. 6, pp. 848-854.e5

  3. Paclitaxel antitumor effect improvement in lung cancer and prevention of the painful neuropathy using large pegylated cationic liposomes

    Biomedicine and Pharmacotherapy, Vol. 133

  4. Sigma-1 receptor: A drug target for the modulation of neuroimmune and neuroglial interactions during chronic pain

    Pharmacological Research, Vol. 163

  5. Tetrodotoxin, a potential drug for neuropathic and cancer pain relief?

    Toxins, Vol. 13, Núm. 7

2020

  1. Editorial: Mechanisms and New Targets for the Treatment of Chronic Pain

    Frontiers in Pharmacology

  2. Sigma-1 receptors control neuropathic pain and macrophage infiltration into the dorsal root ganglion after peripheral nerve injury

    FASEB Journal, Vol. 34, Núm. 4, pp. 5951-5966

  3. The search for translational pain outcomes to refine analgesic development: Where did we come from and where are we going?

    Neuroscience and Biobehavioral Reviews, Vol. 113, pp. 238-261

  4. Urinary bladder sigma-1 receptors: A new target for cystitis treatment

    Pharmacological Research, Vol. 155

2019

  1. Sigma-1 receptor inhibition reduces neuropathic pain induced by partial sciatic nerve transection in mice by opioid-dependent and -independent mechanisms

    Frontiers in Pharmacology, Vol. 10, Núm. JUN

  2. Tetrahydro-3-benzazepines with fluorinated side chains as NMDA and σ1 receptor antagonists: Synthesis, receptor affinity, selectivity and antiallodynic activity

    European Journal of Medicinal Chemistry, Vol. 177, pp. 47-62

2018

  1. Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling

    Cell Reports, Vol. 22, Núm. 5, pp. 1301-1312

  2. Synthesis, Receptor Affinity, and Antiallodynic Activity of Spirocyclic σ Receptor Ligands with Exocyclic Amino Moiety

    Journal of Medicinal Chemistry, Vol. 61, Núm. 21, pp. 9666-9690

  3. Targeting immune-driven opioid analgesia by sigma-1 receptors: Opening the door to novel perspectives for the analgesic use of sigma-1 antagonists

    Pharmacological Research, Vol. 131, pp. 224-230

2017

  1. Effects of tetrodotoxin in mouse models of visceral pain

    Marine Drugs, Vol. 15, Núm. 6

  2. Inflammatory pain control by blocking oxidized phospholipid-mediated TRP channel activation

    Scientific Reports, Vol. 7, Núm. 1

  3. Roles for CD8+T cells and IL-10 in the resolution of paclitaxel-induced neuropathic pain

    Journal of Neuroscience