FRANCISCO RAFAEL
NIETO LÓPEZ
PROFESOR TITULAR DE UNIVERSIDAD
Publicacións (36) Publicacións de FRANCISCO RAFAEL NIETO LÓPEZ
2023
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Conformationally Restricted σ1 Receptor Antagonists from (−)-Isopulegol
Journal of Medicinal Chemistry, Vol. 66, Núm. 7, pp. 4999-5020
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Efficacy and Security of Tetrodotoxin in the Treatment of Cancer-Related Pain: Systematic Review and Meta-Analysis
Marine Drugs, Vol. 21, Núm. 5
2022
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Synthesis of tropane-based σ1 receptor antagonists with antiallodynic activity
European Journal of Medicinal Chemistry, Vol. 230
2021
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Chemoenzymatic synthesis of 2,6-disubstituted tetrahydropyrans with high σ1 receptor affinity, antitumor and analgesic activity
European Journal of Medicinal Chemistry, Vol. 219
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Discovery of a σ1 receptor antagonist by combination of unbiased cell painting and thermal proteome profiling
Cell Chemical Biology, Vol. 28, Núm. 6, pp. 848-854.e5
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Paclitaxel antitumor effect improvement in lung cancer and prevention of the painful neuropathy using large pegylated cationic liposomes
Biomedicine and Pharmacotherapy, Vol. 133
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Sigma-1 receptor: A drug target for the modulation of neuroimmune and neuroglial interactions during chronic pain
Pharmacological Research, Vol. 163
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Tetrodotoxin, a potential drug for neuropathic and cancer pain relief?
Toxins, Vol. 13, Núm. 7
2020
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Editorial: Mechanisms and New Targets for the Treatment of Chronic Pain
Frontiers in Pharmacology
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Sigma-1 receptors control neuropathic pain and macrophage infiltration into the dorsal root ganglion after peripheral nerve injury
FASEB Journal, Vol. 34, Núm. 4, pp. 5951-5966
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The search for translational pain outcomes to refine analgesic development: Where did we come from and where are we going?
Neuroscience and Biobehavioral Reviews, Vol. 113, pp. 238-261
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Urinary bladder sigma-1 receptors: A new target for cystitis treatment
Pharmacological Research, Vol. 155
2019
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Sigma-1 receptor inhibition reduces neuropathic pain induced by partial sciatic nerve transection in mice by opioid-dependent and -independent mechanisms
Frontiers in Pharmacology, Vol. 10, Núm. JUN
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Tetrahydro-3-benzazepines with fluorinated side chains as NMDA and σ1 receptor antagonists: Synthesis, receptor affinity, selectivity and antiallodynic activity
European Journal of Medicinal Chemistry, Vol. 177, pp. 47-62
2018
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Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling
Cell Reports, Vol. 22, Núm. 5, pp. 1301-1312
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Synthesis, Receptor Affinity, and Antiallodynic Activity of Spirocyclic σ Receptor Ligands with Exocyclic Amino Moiety
Journal of Medicinal Chemistry, Vol. 61, Núm. 21, pp. 9666-9690
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Targeting immune-driven opioid analgesia by sigma-1 receptors: Opening the door to novel perspectives for the analgesic use of sigma-1 antagonists
Pharmacological Research, Vol. 131, pp. 224-230
2017
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Effects of tetrodotoxin in mouse models of visceral pain
Marine Drugs, Vol. 15, Núm. 6
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Inflammatory pain control by blocking oxidized phospholipid-mediated TRP channel activation
Scientific Reports, Vol. 7, Núm. 1
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Roles for CD8+T cells and IL-10 in the resolution of paclitaxel-induced neuropathic pain
Journal of Neuroscience