MARIO
CANO MUÑOZ
Forscher in der Zeit 2022-2023
Publikationen (14) Publikationen von MARIO CANO MUÑOZ
2024
-
Investigating vulnerability of the conserved SARS-CoV-2 spike's heptad repeat 2 as target for fusion inhibitors using chimeric miniproteins
International Journal of Biological Macromolecules, Vol. 262
-
Phosphorylation of cytosolic hPGK1 affects protein stability and ligand binding: implications for its subcellular targeting in cancer
FEBS Journal
-
Selective Formation of Pd-DNA Hybrids Using Tailored Palladium-Mediated Base Pairs: Towards Heteroleptic Pd-DNA Systems
Angewandte Chemie - International Edition, Vol. 63, Núm. 11
2022
-
Conformational Stabilization of Gp41-Mimetic Miniproteins Opens Up New Ways of Inhibiting HIV-1 Fusion
International Journal of Molecular Sciences, Vol. 23, Núm. 5
-
Exploring Highly Conserved Regions of SARS-CoV-2 Spike S2 Subunit as Targets for Fusion Inhibition Using Chimeric Proteins
International journal of molecular sciences, Vol. 23, Núm. 24
-
Loss of stability and unfolding cooperativity in hPGK1 upon gradual structural perturbation of its N-terminal domain hydrophobic core
Scientific Reports, Vol. 12, Núm. 1
-
Novel chimeric proteins mimicking SARS-CoV-2 spike epitopes with broad inhibitory activity
International Journal of Biological Macromolecules, Vol. 222, pp. 2467-2478
2021
-
Conformational flexibility of the conserved hydrophobic pocket of HIV-1 gp41. Implications for the discovery of small-molecule fusion inhibitors
International Journal of Biological Macromolecules, Vol. 192, pp. 90-99
-
Extremely thermostabilizing core mutations in coiled‐coil mimetic proteins of hiv‐1 gp41 produce diverse effects on target binding but do not affect their inhibitory activity
Biomolecules, Vol. 11, Núm. 4
2020
-
Naturally-occurring rare mutations cause mild to catastrophic effects in the multifunctional and cancer-associated NQO1 protein
Journal of Personalized Medicine, Vol. 10, Núm. 4, pp. 1-31
-
Probing Vulnerability of the gp41 C-Terminal Heptad Repeat as Target for Miniprotein HIV Inhibitors
Journal of Molecular Biology, Vol. 432, Núm. 20, pp. 5577-5592
-
Thermodynamic dissection of the interface between HIV-1 gp41 heptad repeats reveals cooperative interactions and allosteric effects
Archives of Biochemistry and Biophysics, Vol. 688
2019
-
Oleanolic Acid Derivatives as Potential Inhibitors of HIV-1 Protease
Journal of Natural Products, Vol. 82, Núm. 10, pp. 2886-2896
-
Structural and Thermodynamic Analysis of HIV-1 Fusion Inhibition Using Small gp41 Mimetic Proteins
Journal of Molecular Biology, Vol. 431, Núm. 17, pp. 3091-3106