Publicaciones (14) Publicaciones de MARIO CANO MUÑOZ

2024

  1. Investigating vulnerability of the conserved SARS-CoV-2 spike's heptad repeat 2 as target for fusion inhibitors using chimeric miniproteins

    International Journal of Biological Macromolecules, Vol. 262

  2. Phosphorylation of cytosolic hPGK1 affects protein stability and ligand binding: implications for its subcellular targeting in cancer

    FEBS Journal

  3. Selective Formation of Pd-DNA Hybrids Using Tailored Palladium-Mediated Base Pairs: Towards Heteroleptic Pd-DNA Systems

    Angewandte Chemie - International Edition, Vol. 63, Núm. 11

2022

  1. Conformational Stabilization of Gp41-Mimetic Miniproteins Opens Up New Ways of Inhibiting HIV-1 Fusion

    International Journal of Molecular Sciences, Vol. 23, Núm. 5

  2. Exploring Highly Conserved Regions of SARS-CoV-2 Spike S2 Subunit as Targets for Fusion Inhibition Using Chimeric Proteins

    International journal of molecular sciences, Vol. 23, Núm. 24

  3. Loss of stability and unfolding cooperativity in hPGK1 upon gradual structural perturbation of its N-terminal domain hydrophobic core

    Scientific Reports, Vol. 12, Núm. 1

  4. Novel chimeric proteins mimicking SARS-CoV-2 spike epitopes with broad inhibitory activity

    International Journal of Biological Macromolecules, Vol. 222, pp. 2467-2478

2021

  1. Conformational flexibility of the conserved hydrophobic pocket of HIV-1 gp41. Implications for the discovery of small-molecule fusion inhibitors

    International Journal of Biological Macromolecules, Vol. 192, pp. 90-99

  2. Extremely thermostabilizing core mutations in coiled‐coil mimetic proteins of hiv‐1 gp41 produce diverse effects on target binding but do not affect their inhibitory activity

    Biomolecules, Vol. 11, Núm. 4

2020

  1. Naturally-occurring rare mutations cause mild to catastrophic effects in the multifunctional and cancer-associated NQO1 protein

    Journal of Personalized Medicine, Vol. 10, Núm. 4, pp. 1-31

  2. Probing Vulnerability of the gp41 C-Terminal Heptad Repeat as Target for Miniprotein HIV Inhibitors

    Journal of Molecular Biology, Vol. 432, Núm. 20, pp. 5577-5592

  3. Thermodynamic dissection of the interface between HIV-1 gp41 heptad repeats reveals cooperative interactions and allosteric effects

    Archives of Biochemistry and Biophysics, Vol. 688

2019

  1. Oleanolic Acid Derivatives as Potential Inhibitors of HIV-1 Protease

    Journal of Natural Products, Vol. 82, Núm. 10, pp. 2886-2896

  2. Structural and Thermodynamic Analysis of HIV-1 Fusion Inhibition Using Small gp41 Mimetic Proteins

    Journal of Molecular Biology, Vol. 431, Núm. 17, pp. 3091-3106