Publications (32) Publications de MÓNICA DÍAZ GAVILÁN

2024

  1. Inhibition of hepatic oxalate overproduction ameliorates metabolic dysfunction-associated steatohepatitis

    Nature Metabolism

2022

  1. Effectiveness of an O-Alkyl Hydroxamate in Dogs with Naturally Acquired Canine Leishmaniosis: An Exploratory Clinical Trial

    Animals, Vol. 12, Núm. 19

  2. Lactate dehydrogenase A inhibitors with a 2,8-dioxabicyclo[3.3.1]nonane scaffold: A contribution to molecular therapies for primary hyperoxalurias

    Bioorganic Chemistry, Vol. 129

  3. New salicylic acid derivatives, double inhibitors of glycolate oxidase and lactate dehydrogenase, as effective agents decreasing oxalate production

    European Journal of Medicinal Chemistry, Vol. 237

2021

  1. Small molecule-based enzyme inhibitors in the treatment of primary hyperoxalurias

    Journal of Personalized Medicine, Vol. 11, Núm. 2, pp. 1-31

2020

  1. O-Alkyl Hydroxamates Display Potent and Selective Antileishmanial Activity

    Journal of Medicinal Chemistry, Vol. 63, Núm. 11, pp. 5734-5751

2019

  1. A nanodelivered Vorinostat derivative is a promising oral compound for the treatment of visceral leishmaniasis

    Pharmacological Research, Vol. 139, pp. 375-383

2018

  1. Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1

    Journal of Medicinal Chemistry, Vol. 61, Núm. 16, pp. 7144-7167

2014

  1. Synthesis of l -octaarginine through microencapsulated palladium-catalyzed allyl ester deprotection

    Synlett, Vol. 25, Núm. 16, pp. 2319-2322

2012

  1. Diversity-oriented synthesis

    Chemical Genomics (Cambridge University Press), pp. 39-59

  2. The selective cytotoxic activity in breast cancer cells by an anthranilic alcohol-derived acyclic 5-fluorouracil O,N-acetal is mediated by endoplasmic reticulum stress-induced apoptosis

    European Journal of Medicinal Chemistry, Vol. 50, pp. 376-382

  3. Two-directional synthesis as a tool for diversityoriented synthesis: Synthesis of alkaloid scaffolds

    Beilstein Journal of Organic Chemistry, Vol. 8, pp. 850-860

2011

  1. Anticancer activity and cDNA microarray studies of a (RS)-1,2,3,5- tetrahydro-4,1-benzoxazepine-3-yl]-6-chloro-9H-purine, and an acyclic (RS)-O,N-acetalic 6-chloro-7H-purine

    European Journal of Medicinal Chemistry, Vol. 46, Núm. 9, pp. 3802-3809

2010

  1. Diversity-oriented synthesis of bicyclic and tricyclic alkaloids

    Chemical Communications, Vol. 46, Núm. 5, pp. 776-778

  2. Evaluación de la implantación de un nuevo recurso didáctico -diapositivas dinámicas- en la asignatura de Química Orgánica en la Licenciatura de Farmacia

    Ars pharmaceutica, Vol. 51, Núm. 2, pp. 191-200

2009

  1. An Introduction to Diversity-Oriented Synthesis

    Linker Strategies in Solid-Phase Organic Synthesis (John Wiley and Sons), pp. 239-262

  2. Oligonucleotide-polyamine conjugates: Influence of length and position of 2′-attached polyamines on duplex stability and antisense effect

    European Journal of Medicinal Chemistry, Vol. 44, Núm. 2, pp. 670-677

  3. Synthesis of unprecedented scaffold diversity

    Angewandte Chemie - International Edition

2008

  1. Anticancer activity of (1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl)-pyrimidines and -purines against the MCF-7 cell line: Preliminary cDNA microarray studies

    Bioorganic and Medicinal Chemistry Letters, Vol. 18, Núm. 4, pp. 1457-1460

  2. Design, synthesis and anticancer activity against the MCF-7 cell line of benzo-fused 1,4-dihetero seven- and six-membered tethered pyrimidines and purines

    Current Medicinal Chemistry, Vol. 15, Núm. 25, pp. 2614-2631