Publications (40) RAFAEL GONZÁLEZ CANO publications

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2024

  1. Editorial: Use of Artificial Intelligence to evaluate drug-related behavioral changes in rodents

    Frontiers in Pharmacology

  2. Pharmacological differences in postoperative cutaneous sensitivity, pain at rest, and movement-induced pain in laparotomized mice

    Biomedicine and Pharmacotherapy, Vol. 180

  3. Quantification of stimulus-evoked tactile allodynia in free moving mice by the chainmail sensitivity test

    Frontiers in Pharmacology, Vol. 15

  4. Sigma-1 Receptors Control Neuropathic Pain and Peripheral Neuroinflammation After Nerve Injury in Female Mice: A Transcriptomic Study

    Journal of Neuroimmune Pharmacology, Vol. 19, Núm. 1

2023

  1. Conformationally Restricted σ1 Receptor Antagonists from (−)-Isopulegol

    Journal of Medicinal Chemistry, Vol. 66, Núm. 7, pp. 4999-5020

  2. Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity

    Journal of Medicinal Chemistry, Vol. 66, Núm. 16, pp. 11447-11463

  3. Minocycline Prevents the Development of Key Features of Inflammation and Pain in DSS-induced Colitis in Mice

    Journal of Pain, Vol. 24, Núm. 2, pp. 304-319

  4. Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands

    ACS Chemical Neuroscience, Vol. 14, Núm. 10, pp. 1845-1858

2022

  1. Automated preclinical detection of mechanical pain hypersensitivity and analgesia

    Pain, Vol. 163, Núm. 12, pp. 2326-2336

  2. Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: Design, synthesis, and pharmacological evaluation

    European Journal of Medicinal Chemistry, Vol. 230

  3. Soluble Epoxide Hydrolase Inhibitors: Design, Synthesis, in vitro Profiling and in vivo Evaluation in Murine Models of Pain

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 36

  4. Synthesis of tropane-based σ1 receptor antagonists with antiallodynic activity

    European Journal of Medicinal Chemistry, Vol. 230

  5. Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors

    Journal of medicinal chemistry, Vol. 65, Núm. 20, pp. 13660-13680

2021

  1. Sigma-1 receptor: A drug target for the modulation of neuroimmune and neuroglial interactions during chronic pain

    Pharmacological Research, Vol. 163

  2. Tetrodotoxin, a potential drug for neuropathic and cancer pain relief?

    Toxins, Vol. 13, Núm. 7

  3. Two independent mouse lines carrying the Nav1.7 I228M gain-of-function variant display dorsal root ganglion neuron hyperexcitability but a minimal pain phenotype

    Pain, Vol. 162, Núm. 6, pp. 1758-1770

2020

  1. El receptor sigma-1: una diana farmacológica que modula las interacciones neuroinmunitarias y neurogliales durante el dolor crónico

    Actualidad en farmacología y terapéutica, Vol. 18, Núm. 3, pp. 173-186

  2. Intracolonic Mustard Oil Induces Visceral Pain in Mice by TRPA1-Dependent and -Independent Mechanisms: Role of Tissue Injury and P2X Receptors

    Frontiers in Pharmacology, Vol. 11

  3. Nonsurgical mouse model of endometriosis-associated pain that responds to clinically active drugs

    Pain, Vol. 161, Núm. 6, pp. 1321-1331

  4. Pain analgesic developments in the genomic era

    Genomics of Pain and Co-Morbid Symptoms (Springer International Publishing), pp. 209-237