FARMACOLOGÍA
Departamento
MARÍA DEL CARMEN
RUIZ CANTERO
Investigadora en el periodo 2023-2023
Publicaciones en las que colabora con MARÍA DEL CARMEN RUIZ CANTERO (16)
2023
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Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity
Journal of Medicinal Chemistry, Vol. 66, Núm. 16, pp. 11447-11463
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Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain
Journal of Medicinal Chemistry, Vol. 66, Núm. 14, pp. 9658-9683
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Sigma-1 receptor agonism exacerbates immune-driven nociception: Role of TRPV1 + nociceptors
Biomedicine and Pharmacotherapy, Vol. 167
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The sigma-1 receptor curtails endogenous opioid analgesia during sensitization of TRPV1 nociceptors
British Journal of Pharmacology, Vol. 180, Núm. 8, pp. 1148-1167
2022
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Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties
ACS Chemical Neuroscience, Vol. 13, Núm. 1, pp. 1-15
2021
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Calmodulin supports trpa1 channel association with opioid receptors and glutamate nmda receptors in the nervous tissue
International Journal of Molecular Sciences, Vol. 22, Núm. 1, pp. 1-21
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El sistema opioide endógeno periférico participa en el efecto antinociceptivo de la pregabalina
Encuentros en Neurociencias (Universidad de Granada), pp. 161-188
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Sigma-1 receptor: A drug target for the modulation of neuroimmune and neuroglial interactions during chronic pain
Pharmacological Research, Vol. 163
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Tetrodotoxin, a potential drug for neuropathic and cancer pain relief?
Toxins, Vol. 13, Núm. 7
2020
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El receptor sigma-1: una diana farmacológica que modula las interacciones neuroinmunitarias y neurogliales durante el dolor crónico
Actualidad en farmacología y terapéutica, Vol. 18, Núm. 3, pp. 173-186
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Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists
ACS Medicinal Chemistry Letters, Vol. 11, Núm. 5, pp. 678-685
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Sigma-1 receptors control neuropathic pain and macrophage infiltration into the dorsal root ganglion after peripheral nerve injury
FASEB Journal, Vol. 34, Núm. 4, pp. 5951-5966
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The search for translational pain outcomes to refine analgesic development: Where did we come from and where are we going?
Neuroscience and Biobehavioral Reviews, Vol. 113, pp. 238-261
2019
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Modulation by sigma-1 receptor of morphine analgesia and tolerance: Nociceptive pain, tactile allodynia and grip strength deficits during joint inflammation
Frontiers in Pharmacology, Vol. 10, Núm. FEB
2018
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Targeting immune-driven opioid analgesia by sigma-1 receptors: Opening the door to novel perspectives for the analgesic use of sigma-1 antagonists
Pharmacological Research, Vol. 131, pp. 224-230
2017
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Sigma-1 receptors control immune-driven peripheral opioid analgesia during inflammation in mice
Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Núm. 31, pp. 8396-8401