Novel strategies for the treatment of visceral pain. Role of voltage-gated sodium channels and enhancement of the opioid-induced analgesia by selective blockade of sigma-1 receptor

  1. Artacho Cordón, Antonia
Dirigida per:
  1. Cruz Miguel Cendán Martínez Director

Universitat de defensa: Universidad de Granada

Fecha de defensa: 05 de d’abril de 2022

Tribunal:
  1. José Manuel Baeyens Cabrera President
  2. Enrique José Cobos del Moral Secretari
  3. Lydia Jiménez Díaz Vocal
  4. Carolina Laura Roza Fernández de Caleya Vocal
  5. Enrique Portillo Salido Vocal
Departament:
  1. FARMACOLOGÍA

Tipus: Tesi

Teseo: 717554 DIALNET lock_openDIGIBUG editor

Resum

The first goal of this Thesis was to evaluate the antinociceptive effects of TTXin three different visceral pain models in mice: the intracolonic administration of both capsaicin and mustard oil; and a model of cyclophosphamideinduced cystitis.