Novel strategies for the treatment of visceral pain. Role of voltage-gated sodium channels and enhancement of the opioid-induced analgesia by selective blockade of sigma-1 receptor

  1. Artacho Cordón, Antonia
Dirigée par:
  1. Cruz Miguel Cendán Martínez Directeur

Université de défendre: Universidad de Granada

Fecha de defensa: 05 avril 2022

Jury:
  1. José Manuel Baeyens Cabrera President
  2. Enrique José Cobos del Moral Secrétaire
  3. Lydia Jiménez Díaz Rapporteur
  4. Carolina Laura Roza Fernández de Caleya Rapporteur
  5. Enrique Portillo Salido Rapporteur
Département:
  1. FARMACOLOGÍA

Type: Thèses

Teseo: 717554 DIALNET lock_openDIGIBUG editor

Résumé

The first goal of this Thesis was to evaluate the antinociceptive effects of TTXin three different visceral pain models in mice: the intracolonic administration of both capsaicin and mustard oil; and a model of cyclophosphamideinduced cystitis.