Novel strategies for the treatment of visceral pain. Role of voltage-gated sodium channels and enhancement of the opioid-induced analgesia by selective blockade of sigma-1 receptor

  1. Artacho Cordón, Antonia
unter der Leitung von:
  1. Cruz Miguel Cendán Martínez Doktorvater

Universität der Verteidigung: Universidad de Granada

Fecha de defensa: 05 von April von 2022

Gericht:
  1. José Manuel Baeyens Cabrera Präsident
  2. Enrique José Cobos del Moral Sekretär
  3. Lydia Jiménez Díaz Vocal
  4. Carolina Laura Roza Fernández de Caleya Vocal
  5. Enrique Portillo Salido Vocal
Fachbereiche:
  1. FARMACOLOGÍA

Art: Dissertation

Zusammenfassung

The first goal of this Thesis was to evaluate the antinociceptive effects of TTXin three different visceral pain models in mice: the intracolonic administration of both capsaicin and mustard oil; and a model of cyclophosphamideinduced cystitis.