Novel strategies for the treatment of visceral pain. Role of voltage-gated sodium channels and enhancement of the opioid-induced analgesia by selective blockade of sigma-1 receptor

  1. Artacho Cordón, Antonia
Dirixida por:
  1. Cruz Miguel Cendán Martínez Director

Universidade de defensa: Universidad de Granada

Fecha de defensa: 05 de abril de 2022

Tribunal:
  1. José Manuel Baeyens Cabrera Presidente
  2. Enrique José Cobos del Moral Secretario
  3. Lydia Jiménez Díaz Vogal
  4. Carolina Laura Roza Fernández de Caleya Vogal
  5. Enrique Portillo Salido Vogal
Departamento:
  1. FARMACOLOGÍA

Tipo: Tese

Resumo

The first goal of this Thesis was to evaluate the antinociceptive effects of TTXin three different visceral pain models in mice: the intracolonic administration of both capsaicin and mustard oil; and a model of cyclophosphamideinduced cystitis.