Novel strategies for the treatment of visceral pain. Role of voltage-gated sodium channels and enhancement of the opioid-induced analgesia by selective blockade of sigma-1 receptor

  1. Artacho Cordón, Antonia
Supervised by:
  1. Cruz Miguel Cendán Martínez Director

Defence university: Universidad de Granada

Fecha de defensa: 05 April 2022

Committee:
  1. José Manuel Baeyens Cabrera Chair
  2. Enrique José Cobos del Moral Secretary
  3. Lydia Jiménez Díaz Committee member
  4. Carolina Laura Roza Fernández de Caleya Committee member
  5. Enrique Portillo Salido Committee member
Department:
  1. FARMACOLOGÍA

Type: Thesis

Teseo: 717554 DIALNET lock_openDIGIBUG editor

Abstract

The first goal of this Thesis was to evaluate the antinociceptive effects of TTXin three different visceral pain models in mice: the intracolonic administration of both capsaicin and mustard oil; and a model of cyclophosphamideinduced cystitis.